Schellekens P C, Bijnen A B, Honing M, Lourens J, de Ruiter P
Afd. Chirurgie, Medisch Centrum Alkmaar.
Ned Tijdschr Geneeskd. 1995 Apr 8;139(14):723-7.
To analyse the impact of the introduction of laparoscopic cholecystectomy on overall morbidity and mortality of gall bladder surgery.
Retrospective study.
Medisch Centrum Alkmaar, Alkmaar.
All cholecystectomies performed in our final 'prelaparoscopic' year 1990 were compared with all cholecystectomies performed in 1992, the year in which laparoscopic cholecystectomy has become a standard procedure, thus eliminating selection bias. The analysis included morbidity and mortality related to all procedures.
In 1990, 173 open cholecystectomies were performed, in 1992 40, and 146 laparoscopic ones; the conversion rate was 4%. The number of patients undergoing investigation for common bile duct stones did not change, but there was a shift from intraoperative cholangiography to preoperative ERCP. In 1992 more endoscopic sphincterotomies were performed (13.5%, versus 5.4% in 1990; p = 0.02). One patient died from complications due to diagnostic ERCP. There was no difference in mortality rate of all procedures taken together, between the two years (3/186 in 1992 (1.6%); 2/173 in 1990 (1.2%)). The morbidity rate of all procedures in 1992 was slightly less than in 1990 (chi 2 = 1.91; p = 0.2). There were no common bile duct injuries caused by laparoscopy. In 1992, the mean operation time was longer than in 1990 (82 versus 46 min; p < 0.001) and the median postoperative hospital stay was significantly shorter than in 1990 (2 versus 6 days; p < 0.001).
Introduction of laparoscopic cholecystectomy was responsible for shorter hospital stays and longer operation times. When common bile duct stones were predicted, endoscopic sphincterotomy was performed more frequently. These changes did not negatively influence morbidity and mortality rates for gall bladder surgery in general.
分析引入腹腔镜胆囊切除术对胆囊手术总体发病率和死亡率的影响。
回顾性研究。
阿尔克马尔医学中心,阿尔克马尔。
将1990年我们最后一个“腹腔镜手术前”年份进行的所有胆囊切除术与1992年进行的所有胆囊切除术进行比较,1992年腹腔镜胆囊切除术已成为标准手术,从而消除了选择偏倚。分析包括与所有手术相关的发病率和死亡率。
1990年进行了173例开腹胆囊切除术,1992年进行了40例,腹腔镜手术146例;转换率为4%。接受胆总管结石检查的患者数量没有变化,但从术中胆管造影转向了术前内镜逆行胰胆管造影(ERCP)。1992年进行内镜括约肌切开术的比例更高(13.5%,而1990年为5.4%;p = 0.02)。1例患者死于诊断性ERCP的并发症。两年间所有手术的总死亡率没有差异(1992年为3/186(1.6%);1990年为2/173(1.2%))。1992年所有手术的发病率略低于1990年(卡方检验=1.91;p = 0.2)。腹腔镜手术未导致胆总管损伤。1992年,平均手术时间比1990年长(82分钟对46分钟;p < 0.001),术后中位住院时间明显短于1990年(2天对6天;p < 0.001)。
引入腹腔镜胆囊切除术导致住院时间缩短和手术时间延长。当预计有胆总管结石时,内镜括约肌切开术的实施更为频繁。总体而言,这些变化并未对胆囊手术的发病率和死亡率产生负面影响。