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对600例行胆囊切除术的患者进行选择性胆管造影,并对残余胆管结石进行5年随访。

Selective cholangiography in 600 patients undergoing cholecystectomy with 5-year follow-up for residual bile duct stones.

作者信息

Charfare H, Cheslyn-Curtis S

机构信息

Department of Surgery, Luton and Dunstable Hospital, Luton, UK.

出版信息

Ann R Coll Surg Engl. 2003 May;85(3):167-73. doi: 10.1308/003588403321661316.

Abstract

BACKGROUND

The need for cholangiography to identify possible bile duct stones in all patients undergoing cholecystectomy is controversial.

AIMS

To assess the results of a policy for selective pre-operative endoscopic retrograde cholangiography (ERC) in patients undergoing laparoscopic cholecystectomy and to determine the incidence of postoperative symptomatic bile duct stones.

PATIENTS AND METHODS

Between 1993 and 1998, 600 patients underwent laparoscopic cholecystectomy under one consultant surgeon. Patients were selected for pre-operative or postoperative ERC based on symptoms, liver function tests and/or abnormalities on ultrasonography. A general practitioner questionnaire was used to assess follow-up of patients with postoperative stones.

RESULTS

Of 600 patients, 107 (18%) with a median age of 57 years and male:female ratio of 1:2.1 were selected to undergo pre-operative ERC; of these, 41 patients (38%) had bile duct stones. Postoperative ERC was performed in 30 patients (5%) and stones were identified in seven (23.3%). Three patients (0.5%) had stones removed within 15 days of operation and four (0.7%) between 2.6 months and 1.8 years. Median follow-up was 5.0 years (range, 2.5-7.5 years). The overall incidence of bile duct stones was 48 cases (8%). The stone rate was 11% in males and 7.3% in females. Stones were successfully extracted at ERC in 43 patients (89.6%).

CONCLUSIONS

A policy of selective pre-operative ERC is the most effective technique for identifying and removing bile duct stones and the incidence of symptomatic gallstones following laparoscopic cholecystectomy is very low. With an overall stone rate of 8%, routine peroperative cholangiography is unnecessary and, in a surgical unit providing an ERC service, laparoscopic exploration of the bile duct is not a technique required for the management of bile duct stones.

摘要

背景

对于所有接受胆囊切除术的患者,是否有必要进行胆管造影以识别可能存在的胆管结石存在争议。

目的

评估一项针对接受腹腔镜胆囊切除术患者的选择性术前内镜逆行胆管造影(ERC)策略的结果,并确定术后有症状胆管结石的发生率。

患者与方法

1993年至1998年间,600例患者在同一位外科顾问医生的操作下接受了腹腔镜胆囊切除术。根据症状、肝功能检查和/或超声检查异常情况,选择患者进行术前或术后ERC。使用全科医生调查问卷对术后结石患者进行随访评估。

结果

600例患者中,107例(18%),中位年龄57岁,男女比例为1:2.1,被选择进行术前ERC;其中,41例患者(38%)有胆管结石。30例患者(5%)进行了术后ERC,7例(23.3%)发现有结石。3例患者(0.5%)在术后15天内取出结石,4例(0.7%)在2.6个月至1.8年之间取出结石。中位随访时间为5.0年(范围2.5 - 7.5年)。胆管结石的总发生率为48例(8%)。男性结石发生率为11%,女性为7.3%。43例患者(89.6%)在ERC时成功取出结石。

结论

选择性术前ERC策略是识别和清除胆管结石最有效的技术,腹腔镜胆囊切除术后有症状胆结石的发生率非常低。总体结石发生率为8%,术中常规胆管造影没有必要,并且在提供ERC服务的手术科室,腹腔镜胆管探查术并非处理胆管结石所需的技术。

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