Moscovitch C, Kapur S, Köhler S, Houle S
Department of Psychology, University of Toronto, Mississauga, ON, Canada.
Proc Natl Acad Sci U S A. 1995 Apr 25;92(9):3721-5. doi: 10.1073/pnas.92.9.3721.
The purpose of the present study was to investigate by using positron emission tomography (PET) whether the cortical pathways that are involved in visual perception of spatial location and object identity are also differentially implicated in retrieval of these types of information from episodic long-term memory. Subjects studied a set of displays consisting of three unique representational line drawings arranged in different spatial configurations. Later, while undergoing PET scanning, subjects' memory for spatial location and identity of the objects in the displays was tested and compared to a perceptual baseline task involving the same displays. In comparison to the baseline task, each of the memory tasks activated both the dorsal and the ventral pathways in the right hemisphere but not to an equal extent. There was also activation of the right prefrontal cortex. When PET scans of the memory tasks were compared to each other, areas of activation were very circumscribed and restricted to the right hemisphere: For retrieval of object identity, the area was in the inferior temporal cortex in the region of the fusiform gyrus (area 37), whereas for retrieval of spatial location, it was in the inferior parietal lobule in the region of the supramarginal gyrus (area 40). Thus, our study shows that distinct neural pathways are activated during retrieval of information about spatial location and object identity from long-term memory.
本研究的目的是通过正电子发射断层扫描（PET）来探究，参与空间位置和物体识别视觉感知的皮质通路，在从情景长期记忆中检索这些类型的信息时是否也存在差异。受试者学习了一组由三个独特的代表性线条图组成的展示，这些线条图以不同的空间配置排列。后来，在进行PET扫描时，测试了受试者对展示中物体的空间位置和身份的记忆，并将其与涉及相同展示的感知基线任务进行比较。与基线任务相比，每个记忆任务都激活了右半球的背侧和腹侧通路，但程度不同。右前额叶皮层也有激活。当将记忆任务的PET扫描相互比较时，激活区域非常局限，且仅限于右半球：对于物体身份的检索，激活区域位于梭状回区域（37区）的颞下回，而对于空间位置的检索，激活区域位于缘上回区域（40区）的顶下小叶。因此，我们的研究表明，在从长期记忆中检索关于空间位置和物体身份的信息时，不同的神经通路会被激活。
