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[巴西米纳斯吉拉斯州拉加马尔绦虫病-囊尾蚴病流行区人群的神经学及实验室检查结果(1992 - 1993年)]

[Neurologic and laboratory findings in a population of an endemic area for taeniasis-cysticercosis, Lagamar, MG, Brazil (1992-1993)].

作者信息

Silva-Vergara M L, Vieira C de O, Castro J H, Micheletti L G, Otaño A S, Franquini júnior J, Cabral M, Leboreiro A, Marques J O, de Souza W F

机构信息

Disciplina de Doenças Infecciosas e Parasitárias, Faculdade de Medicina do Triângulo Mineiro (FMTM), Uberaba/MG, Brasil.

出版信息

Rev Inst Med Trop Sao Paulo. 1994 Jul-Aug;36(4):335-42. doi: 10.1590/s0036-46651994000400006.

DOI:10.1590/s0036-46651994000400006
PMID:7732264
Abstract

A clinic-epidemiological enquiry was conducted on in an endemic area for teniasis-cysticercosis. From the whole population 1080 (32.2%) individuals were examined. We found 198 (18.3%) individuals referring teniasis-bearing in the past, and 103 (9.5%) affirming to have had convulsions, either in the past or present. From the last group, 39 (37.8%) indicated that the crisis had begun in adulthood. From the group of patients presenting convulsions, 62 (62%) had laboratory tests performed. Computed tomography showed intracranial calcifications in 21 (33.8%) patients, variable in number and location, suggesting neurocysticercosis and no evidence of disease activity. Electroencephalograms showed abnormal waves in 21 (33.8%) patients and cerebrospinal fluid analyses were altered in 27 (43.5%) cases, having detected eosinophils only in 3 (4.8%) patients. Spinal fluid tests for cysticercosis through enzyme linked immunosorbent assay (ELISA) or indirect immunofluorescence were taken in only 26 (41.9%) patients, obtaining positive results in 6 (23%) samples. Varying upward shifts of protein levels were found in spinal fluid analysis. Assuming that all epidemiologic risk factors for teniasis-cysticercosis in the studied region and its correlation with the laboratory alterations described in convulsing crisis, a prevalence of 1.9% for neurocysticercosis was found.

摘要

在绦虫病-囊尾蚴病流行地区进行了一项临床流行病学调查。对整个人口的1080人(32.2%)进行了检查。我们发现198人(18.3%)曾患绦虫病,103人(9.5%)确认过去或现在有过惊厥。在最后一组中,39人(37.8%)表示惊厥始于成年期。在出现惊厥的患者组中,62人(62%)进行了实验室检查。计算机断层扫描显示21名患者(33.8%)颅内有钙化,数量和位置各不相同,提示神经囊尾蚴病且无疾病活动迹象。脑电图显示21名患者(33.8%)有异常波,脑脊液分析在27例(43.5%)中发生改变,仅在3例(4.8%)患者中检测到嗜酸性粒细胞。仅26名患者(41.9%)进行了通过酶联免疫吸附测定(ELISA)或间接免疫荧光法检测囊尾蚴病的脑脊液检查,6份样本(23%)呈阳性。脑脊液分析中发现蛋白质水平有不同程度的上升。假设研究区域内绦虫病-囊尾蚴病的所有流行病学危险因素及其与惊厥发作时所描述的实验室改变的相关性,神经囊尾蚴病的患病率为1.9%。

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