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中枢神经系统和脑脊液囊尾蚴病。63年(1929 - 1992年)间1573例患者的免疫诊断

Cysticercosis of the central nervous system and cerebrospinal fluid. Immunodiagnosis of 1573 patients in 63 years (1929-1992).

作者信息

Spina-França A, Livramento J A, Machado L R

机构信息

CIN, Centro de Investigações em Neurologia, Faculdade de Medicina da Universidade de São Paulo (FMUSP), Brasil.

出版信息

Arq Neuropsiquiatr. 1993 Mar;51(1):16-20. doi: 10.1590/s0004-282x1993000100003.

DOI:10.1590/s0004-282x1993000100003
PMID:8215925
Abstract

Attention given to prophylaxis of neurocysticercosis (NC) is far beyond minimal needs among several regions of the in-development world, and for this reason incidence of the disease persists high among them. This investigation was carried out to show the extent of the problem by analysing the incidence of NC in a region of Brazil (São Paulo). CSF immunodiagnosis of NC by detecting antibodies to Cysticercus cellulosae in a neurodiagnostics laboratory is evaluated for this purpose. Cases studied in a 63-year period (1929-1992) are reviewed. Total cases in this period is 139,000, and for 1,573 (1.13%) diagnosis is NC. Special characteristics were not detected for colour and sex prevalence. Age bracket prevalence is from 21 to 40 years old (55.3%) high rates occurring for women between 21 to 30 years old, and for men between 31 to 40. Cases distribution in five consecutive decades (1942-1991) shows no decreasing tendency: average incidence is 1% for the 50 years, and it is over this average for the last three decades. Data confirm that incidence continues expressively high throughout the 50 years covered by this study.

摘要

在发展中世界的几个地区,对神经囊尾蚴病(NC)预防的关注远远超过了最低需求,因此该病在这些地区的发病率一直居高不下。本研究旨在通过分析巴西圣保罗州一个地区的NC发病率来揭示该问题的严重程度。为此,对一家神经诊断实验室通过检测针对猪囊尾蚴的抗体进行NC的脑脊液免疫诊断进行了评估。回顾了63年(1929 - 1992年)期间研究的病例。该时期的病例总数为139,000例,其中1,573例(1.13%)诊断为NC。未发现颜色和性别患病率的特殊特征。年龄组患病率在21至40岁之间(55.3%),21至30岁的女性和31至40岁的男性患病率较高。连续五个十年(1942 - 1991年)的病例分布没有下降趋势:50年的平均发病率为1%,过去三十年高于此平均水平。数据证实,在本研究涵盖的50年中,发病率一直居高不下。

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