Botet Fregola J, Portús Vinyeta M
Laboratorio de Parasitología, Facultad de Farmacia, Universidad de Barcelona.
Rev Sanid Hig Publica (Madr). 1993 Jul-Aug;67(4):255-66.
A bibliographic-historical review of leishmaniasis in Spain during the period 1912-1985 is carried out. The bibliographical prospecting has allowed to collect a total of 402 works; out of them only 79 are included in this review. From reading them, it can be deduced that, starting from its discovery in the coast of Levante in 1912, leishmaniasis has been a very well known disease in Spain, during the first third of our century, period in which a remarkable prevalence took place, as it follows from the works published basically by Pittaluga and colleagues. In them, plentiful clinical and epidemiologic data are collected, many of them having laid the foundations of this disease knowledge in our country. Nevertheless, the extrapolation of data from other geographical regions introduced confusions, which have continued till recent time, basically on what refers to the existing relation between the aetiological agent and the clinical case. On the other hand, nowadays, current important matters such as the part of person's immune response in the appearance of a visceral or cutaneous case of leishmaniasis, independently from the parasites specific identity or the presence of asymptomatic leishmaniasis, are already found in pioneer works. In the course of the work, a review is made of the information, obtained form the Spanish bibliography, on the leishmaniasis aetiological agent in Spain, the vector and the host as well as the various clinical cases of human and canine leishmaniasis, their epidemiology, diagnostic and treatment.
对1912年至1985年期间西班牙利什曼病进行了文献历史回顾。文献检索共收集到402篇著作;其中仅79篇纳入本综述。通过阅读这些文献可以推断,自1912年在巴伦西亚海岸发现利什曼病以来,在20世纪上半叶,利什曼病在西班牙一直是一种广为人知的疾病,当时该病有显著的流行率,这从基本上由皮塔卢加及其同事发表的著作中可以看出。在这些著作中收集了丰富的临床和流行病学数据,其中许多为我国对该疾病的认识奠定了基础。然而,从其他地理区域推断的数据造成了混乱,这种混乱一直持续到最近,主要涉及病原体与临床病例之间的现有关系。另一方面,如今,一些重要的问题,如在利什曼病内脏型或皮肤型病例出现时人的免疫反应所起的作用,独立于寄生虫的具体特性或无症状利什曼病的存在,在早期著作中已经有所涉及。在这项工作过程中,对从西班牙文献中获得的关于西班牙利什曼病病原体、传播媒介和宿主以及人类和犬类利什曼病的各种临床病例、其流行病学、诊断和治疗的信息进行了综述。