组蛋白非酶糖基化的差异。
Differences in nonenzymatic glycation of histones.
作者信息
Lakatos A, Kiss N, Jobst K
机构信息
Department of Clinical Chemistry, University Medical School, Pécs, Hungary.
出版信息
Acta Biochim Pol. 1994;41(4):429-32.
PMID:7732760
Abstract
Time course of glucose binding by histone Hl and total histones was followed in isolated histone preparations and in thymus nuclei. In both cases the uptake of glucose by Hl was surprisingly high in contrast to a much lower uptake of glucose by total histones. DNA is not implicated in glycation of histones in nuclei.
摘要
在分离的组蛋白制剂和胸腺细胞核中，对组蛋白H1和总组蛋白与葡萄糖结合的时间进程进行了跟踪。在这两种情况下，与总组蛋白对葡萄糖的摄取量低得多形成对比的是，H1对葡萄糖的摄取量出奇地高。DNA与细胞核中组蛋白的糖基化无关。
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