Smith M D, Cassidy J M, Gurley J C, Smith A C, Booth D C
Division of Cardiology, College of Medicine, University of Kentucky, Lexington 40536-0084, USA.
Am Heart J. 1995 May;129(5):967-74. doi: 10.1016/0002-8703(95)90118-3.
Acute mitral regurgitation is a medical emergency that requires prompt, accurate diagnosis and urgent therapy. Although the use of echo Doppler imaging has been described in these patients, preliminary observations have suggested that color flow Doppler performed from the standard transthoracic windows may underestimate the severity of mitral insufficiency in this setting. The aim of this study was to compare transesophageal color Doppler quantitation of regurgitation with results obtained from standard transthoracic windows in patients with acute, severe mitral regurgitation. Two-dimensional echocardiography with pulsed, continuous, and color flow Doppler was performed by both transthoracic and transesophageal methods in 16 consecutive patients who were documented to have acute severe mitral insufficiency by catheterization. Transthoracic and transesophageal scans were reviewed by two blinded observers and assessed for the detection of mitral regurgitation by transthoracic pulsed wave (81%), continuous wave (100%), and color flow Doppler (81%) compared with transesophageal color flow imaging (100%; p = NS). Severity of mitral regurgitation was graded as none, mild, moderate, or severe on the basis of existing transthoracic pulsed wave and color flow criteria and compared with transesophageal color flow grading. At first examination patients were critically ill, with elevated pulmonary wedge pressures (mean 27 +/- 7 mm Hg) and V waves (mean 45 +/- 10 mm Hg). Fifteen of the patients underwent emergency surgery, and the overall hospital mortality rate was 12%. Maximal color flow jet areas were significantly greater on transesophageal scanning (mean 10.5 cm2) compared with transthoracic color jets (mean 2.3 cm2).(ABSTRACT TRUNCATED AT 250 WORDS)
急性二尖瓣反流是一种需要迅速、准确诊断及紧急治疗的医疗急症。尽管已在这些患者中描述了使用超声多普勒成像,但初步观察表明,从标准经胸窗口进行的彩色血流多普勒检查可能会低估这种情况下二尖瓣关闭不全的严重程度。本研究的目的是比较急性重度二尖瓣反流患者经食管彩色多普勒反流定量与从标准经胸窗口获得的结果。对16例经心导管检查证实患有急性重度二尖瓣关闭不全的连续患者,采用经胸和经食管方法进行二维超声心动图检查,包括脉冲波、连续波和彩色血流多普勒检查。两名盲法观察者对经胸和经食管扫描进行评估,比较经胸脉冲波(81%)、连续波(100%)和彩色血流多普勒(81%)检测二尖瓣反流的情况与经食管彩色血流成像(100%;p=无显著差异)。根据现有的经胸脉冲波和彩色血流标准,将二尖瓣反流的严重程度分为无、轻度、中度或重度,并与经食管彩色血流分级进行比较。初次检查时患者病情危重,肺楔压升高(平均27±7mmHg)和V波(平均45±10mmHg)。15例患者接受了急诊手术,总体医院死亡率为12%。与经胸彩色血流束(平均2.3cm²)相比,经食管扫描的最大彩色血流束面积显著更大(平均10.5cm²)。(摘要截短至250字)