Stringa S G, Bianchi C, Andrada J A, Comini E, Gaviglio A M, Casalá A
Arch Dermatol. 1976 Apr;112(4):489-92.
Immunologic response to A and B erythrocytic antigen stimulation was studied in patients with pemphigus, in patients with systemic lupus erythematosus (SLE), and in normal subjects. Patients with pemphigus and normal subjects demonstrated a similar specific response (isohemagglutinins). A comparison between patients with pemphigus and SLE showed higher titers in the latter. Intercellular antibody titers increased after stimulation; corresponding titers were unaffected by isohemagglutinin absorption. Direct immunofluorescent studies showed IgG deposits in the intercellular spaces of the skin of the patients with pemphigus. However, C3 was found in the same sites in only three cases of pemphigus erythematosus. Immunofluorescent studies for IgG at the basal membrane were positive in only two cases of pemphigus erythematosus. Immunologic response of patients with pemphigus was similar to that of controls; however, it differed from that of patients with SLE.
对天疱疮患者、系统性红斑狼疮（SLE）患者和正常受试者进行了针对A和B红细胞抗原刺激的免疫反应研究。天疱疮患者和正常受试者表现出相似的特异性反应（同种血凝素）。天疱疮患者与SLE患者的比较显示，后者的滴度更高。刺激后细胞间抗体滴度升高；相应滴度不受同种血凝素吸收的影响。直接免疫荧光研究显示，天疱疮患者皮肤的细胞间间隙中有IgG沉积。然而，仅在三例红斑性天疱疮患者的相同部位发现了C3。仅两例红斑性天疱疮患者的基底膜IgG免疫荧光研究呈阳性。天疱疮患者的免疫反应与对照组相似；然而，它与SLE患者的免疫反应不同。
