Treloar P H, Christie I M, Vadgama P M
University of Manchester, Department of Medicine, Hope Hospital, Salford, UK.
Biosens Bioelectron. 1995;10(1-2):195-201. doi: 10.1016/0956-5663(95)96806-a.
A generic approach to adapting many sensors to the rigours of biomedical measurement is to protect appropriate components with selective solute discriminating membrane layers. Our work has utilised external barrier membranes for mass transport control to enzyme electrodes in order to adapt their behaviour to requisite clinical ranges; these membranes have had the additional important effect of reducing surface deposition of colloid and other material on electrode surfaces. Internal membranes, especially those interposed between the enzyme layer and the working electrode of an amperometric sensor, have been found by us to be remarkably important in determining sensor operational stability. This paper will review such membrane materials, including coating technologies, and suggest appropriate directions for future work.
使多种传感器适应生物医学测量严苛要求的通用方法是，用具有选择性溶质区分功能的膜层保护合适的部件。我们的工作利用外部屏障膜来控制传质至酶电极，以使它们的行为适应所需的临床范围；这些膜还具有减少胶体和其他物质在电极表面沉积的重要额外作用。我们发现，内膜，尤其是介于酶层和电流型传感器工作电极之间的内膜，在决定传感器操作稳定性方面非常重要。本文将综述这类膜材料，包括涂层技术，并为未来工作提出合适的方向。
