Blanco-López M C, Gutiérrez-Fernández S, Lobo-Castañón M J, Miranda-Ordieres A J, Tuñón-Blanco P
Departamento de Química Física y Analítica, Facultad de Química, Universidad de Oviedo, C/Julián Clavería 8, 33006 Oviedo, Spain.
Anal Bioanal Chem. 2004 Apr;378(8):1922-8. doi: 10.1007/s00216-003-2330-2. Epub 2003 Dec 20.
This article summarises our work on the development of voltammetric sensors based on molecularly imprinted polymers. Several recognition elements and integration strategies were used:1.membranes electropolymerised at the electrode surface; 2.casting of polymeric membranes by drop-coating a solution of pre-formed polymer (polyphosphazene) and template in a low-boiling-point solvent on to the electrode surface; 3.preparation of composite membranes containing conductive material (graphite or carbon black), acrylic-type molecularly imprinted polymers (small particle size), and PVC as binder; and 4.in-situ polymerisation of a thin layer of acrylic imprinted polymer deposited on the electrode surface by spin coating. All the options evaluated offer the possibility of controlling electrode characteristics such as hydrophobic/hydrophilic character, permeability, or film thickness, which are essential for obtaining good sensor performance.
本文总结了我们在基于分子印迹聚合物的伏安传感器开发方面的工作。我们采用了几种识别元件和集成策略：1. 在电极表面进行电聚合的膜；2. 通过将预成型聚合物（聚磷腈）和模板的溶液滴涂在低沸点溶剂中并涂覆到电极表面上来浇铸聚合物膜；3. 制备包含导电材料（石墨或炭黑）、丙烯酸型分子印迹聚合物（小粒径）和PVC作为粘合剂的复合膜；4. 通过旋涂在电极表面沉积一层丙烯酸印迹聚合物薄层进行原位聚合。所评估的所有选项都提供了控制电极特性（如疏水/亲水特性、渗透性或膜厚度）的可能性，这些特性对于获得良好的传感器性能至关重要。
