Thornton A R
MRC Institute of Hearing Research, Royal South Hants Hospital, Southampton, UK.
Br J Audiol. 1994 Aug-Oct;28(4-5):227-34. doi: 10.3109/03005369409086572.
A previous study has shown that the amplitude of otoacoustic emissions decreases with increase in stimulus rate. Furthermore, these changes are similar to the changes initiated by contralateral suppression of the click-evoked otoacoustic emission. Further studies have been carried out which showed that contralateral suppression, due to a 60 dB SL white-noise suppressor, has a magnitude of about 2.7 dB for the normal subjects used in this study. The equivalent ipsilateral 'suppression' is approximately 8 dB at a stimulus rate of 2000 clicks/s. The two effects have an equivalent magnitude at a stimulus rate of approximately 300 clicks/s. In acoustic neuroma patients, where the nerve pathway is impeded by the tumour, the ipsilateral 'suppression' effect is virtually absent. These findings suggest that an ipsilateral 'suppression' similar in form but larger in magnitude than the more usual contralateral suppression can be created by increasing the stimulus rate using maximum length sequence (MLS) techniques.
先前的一项研究表明,耳声发射的幅度会随着刺激速率的增加而降低。此外,这些变化类似于对咔嗒声诱发耳声发射进行对侧抑制所引发的变化。已经开展了进一步的研究,结果显示,对于本研究中使用的正常受试者,由于60 dB SL白噪声抑制器导致的对侧抑制幅度约为2.7 dB。在2000次咔嗒声/秒的刺激速率下,等效的同侧“抑制”约为8 dB。在大约300次咔嗒声/秒的刺激速率下,这两种效应的幅度相当。在听神经瘤患者中,神经通路被肿瘤阻碍,同侧“抑制”效应实际上不存在。这些发现表明,通过使用最大长度序列(MLS)技术提高刺激速率,可以产生一种形式上与通常的对侧抑制相似但幅度更大的同侧“抑制”。