Emberton M, Neal D E, Black N, Harrison M, Fordham M, McBrien M P, Williams R E, McPherson K, Devlin H B
Surgical Epidemiology and Audit Unit, Royal College of Surgeons of England, University of Newcastle Upon Tyne, UK.
Br J Urol. 1995 Mar;75(3):301-16. doi: 10.1111/j.1464-410x.1995.tb07341.x.
To determine everyday practice in the hospital management of men undergoing prostatectomy and the extent of its variation.
A total of 5361 patients, who represented 89% of all those undergoing prostatic procedures in four health regions (Mersey, Wessex, Northern and South West Thames) and one test site (within Trent) were recruited by 103 (97%) surgeons. Clinical information was collected on a pre-coded data collection form which was completed during the hospital stay by the principal operator. Patient identification occurred at the time of surgery.
Important findings included: (i) both older men and those of higher social class were more likely to undergo prostatectomy with fewer symptoms; (ii) men who waited longer for surgery had worse symptoms by the time of their operation; (iii) there were unexplained differences in routine pre- and post-operative investigation and treatment. Half the men had their flow rate or residual urine measured as part of their pre-operative assessment. About half the men received prophylactic antibiotics; (iv) when large groups were analysed, a consistent proportion of men throughout the study (12%) were undergoing the operation for a second time. The clinical course of men having a repeat operation differed in many ways from those having a first time procedure; (v) the larger proportion of men (62%) had surgery for strong indications as opposed to symptoms alone; (vi) although most operations were performed by consultants, emergency admissions, though symptomatically more severe and sicker, were more likely to be operated on by trainee surgeons; (vii) significant variation in mean pre-operative symptom severity and bother scores were seen between surgeons.
The clinical management of prostatectomy has been defined in a large and representative UK sample. In some circumstances consistent variations have been identified. It is not yet clear whether these variations influence outcome. These data can be used by surgeons wishing to compare their own patient management with that described here.
确定前列腺切除术后男性患者在医院管理中的日常实践及其变化程度。
103位(97%)外科医生招募了总共5361名患者,这些患者占四个健康区域(默西、韦塞克斯、北部和泰晤士西南)以及一个试验地点(特伦特地区内)所有接受前列腺手术患者的89%。临床信息通过预先编码的数据收集表收集,由主刀医生在患者住院期间填写。患者身份识别在手术时进行。
重要发现包括:(i)老年男性和社会阶层较高的男性更有可能在症状较少时接受前列腺切除术;(ii)等待手术时间较长的男性在手术时症状更严重;(iii)术前和术后常规检查与治疗存在无法解释的差异。一半的男性在术前评估时测量了尿流率或残余尿量。约一半的男性接受了预防性抗生素治疗;(iv)在对大样本进行分析时,整个研究中始终有12%的男性接受二次手术。接受二次手术的男性的临床过程在许多方面与首次手术的男性不同;(v)较大比例的男性(62%)接受手术是因为有强烈指征,而非仅因症状;(vi)尽管大多数手术由顾问医生进行,但急诊入院患者虽然症状更严重、病情更重,但更有可能由实习外科医生进行手术;(vii)外科医生之间术前平均症状严重程度和困扰评分存在显著差异。
在一个具有代表性的英国大样本中明确了前列腺切除术的临床管理情况。在某些情况下已确定了一致的差异。目前尚不清楚这些差异是否会影响治疗结果。希望将自己的患者管理与本文所述情况进行比较的外科医生可以使用这些数据。