生长后备母猪（猪）对乙酸盐、丙酸盐、正丁酸盐和葡萄糖急性刺激的血浆胰岛素和胰高血糖素反应。

Plasma insulin and glucagon responses to acute challenges of acetate, propionate, n-butyrate and glucose in growing gilts (Sus scrofa).

作者信息

Sano H, Nakamura E, Takahashi H, Terashima Y

机构信息

Faculty of Animal Science, Kitasato University, Japan.

出版信息

Comp Biochem Physiol A Physiol. 1995 Apr;110(4):375-8. doi: 10.1016/0300-9629(94)00155-m.

DOI:10.1016/0300-9629(94)00155-m

PMID:7735905

Abstract

A supraphysiological dose (2.5 mmol kg-1 body weight) of acetate, propionate, n-butyrate or glucose was intravenously injected to measure plasma insulin and glucagon responses in growing gilts. Plasma insulin concentrations remained constant after injection of the volatile fatty acids. Plasma glucagon concentrations increased (P < 0.05) after n-butyrate injection following an initial temporary decrease (P < 0.05), and showed a similar tendency after acetate or propionate injection. These results suggest that a supraphysiological dose of acetate, propionate or n-butyrate may stimulate a plasma glucagon response in growing piglets.

摘要

向生长中的后备母猪静脉注射超生理剂量（2.5 mmol/kg体重）的乙酸盐、丙酸盐、正丁酸盐或葡萄糖，以测量血浆胰岛素和胰高血糖素反应。注射挥发性脂肪酸后，血浆胰岛素浓度保持不变。注射正丁酸盐后，血浆胰高血糖素浓度在最初短暂下降（P<0.05）后升高（P<0.05），注射乙酸盐或丙酸盐后也呈现类似趋势。这些结果表明，超生理剂量的乙酸盐、丙酸盐或正丁酸盐可能会刺激生长中小猪的血浆胰高血糖素反应。