Drummond P D
Psychology Section, Murdoch University, Western Australia.
J Auton Nerv Syst. 1995 Feb 9;51(2):109-16. doi: 10.1016/0165-1838(94)00121-y.
The effect of painful stimulation of the nasal ala and upper lip on lacrimation and cutaneous vascular responses in the forehead and cheeks was investigated in 11 normal subjects. In addition, the mechanism of the response was studied in 10 patients with a lesion compromising parasympathetic activity in the facial nerve. In normal subjects, pinching the nasal ala with forceps increased blood flow on the ipsilateral side of the forehead but not the cheek. Pinching the upper-lip induced ipsilateral vasodilation in the forehead in 3 of 11 subjects, but not in the cheek. Pinching either site increased corneal moisture proportional to the size of the vascular response in the forehead. A facial nerve lesion inhibited the ipsilateral component of the vascular response in the forehead. These findings suggest that pain within the distribution of the first or second divisions of the trigeminal nerve excites vasodilator and lacrimal reflexes in the facial nerve. The increase in cutaneous flow during this trigeminal-parasympathetic reflex appears to be limited to the forehead.
在11名正常受试者中，研究了鼻翼和上唇的疼痛刺激对前额和脸颊的流泪及皮肤血管反应的影响。此外，还对10名面神经副交感神经活动受损的患者的反应机制进行了研究。在正常受试者中，用镊子捏鼻翼会增加前额同侧的血流量，但脸颊血流量无变化。捏上唇在11名受试者中有3名引起前额同侧血管扩张，但脸颊未出现。捏任何一个部位都会使角膜湿度增加，且与前额血管反应的大小成正比。面神经损伤会抑制前额血管反应的同侧成分。这些发现表明，三叉神经第一或第二分支分布区域内的疼痛会激发面神经中的血管舒张和流泪反射。这种三叉神经 - 副交感神经反射期间皮肤血流量的增加似乎仅限于前额。
