Drummond P D
Psychology Section, Murdoch University, Western Australia.
Brain. 1992 Oct;115 ( Pt 5):1417-28. doi: 10.1093/brain/115.5.1417.
The vascular response in the forehead and cheeks to irritating the eye with soapy water was measured in 15 normal subjects. Electrodermal activity, which reflects sweating, was also measured from both sides of the forehead. The mechanism of the response was studied in 15 patients with a unilateral lesion of the facial nerve blocking parasympathetic outflow. Pulse amplitude usually increased briefly on both sides of the forehead after the soap was placed in the eye; the response persisted for several minutes on the ipsilateral side after the soap had been washed from the eye. A facial nerve lesion blocked the vascular response on the lesioned side to stimulation of either eye. No consistent change in pulse amplitude was recorded from the cheeks, although a response was observed in a few subjects. Electrodermal responses to ocular irritation were generally larger on the ipsilateral than contralateral side of the forehead; in patients with facial palsy, electrodermal responses were greater on the normally innervated side than on the lesioned side. The findings suggest that irritating the eye induces a trigeminal-parasympathetic vasodilator reflex and local sweating. The restricted distribution of the response indicates that separate parasympathetic vasodilator reflexes might operate for each division of the trigeminal nerve.
在15名正常受试者中测量了前额和脸颊对用肥皂水刺激眼睛的血管反应。还从前额两侧测量了反映出汗情况的皮肤电活动。在15例因面神经单侧病变而阻断副交感神经传出的患者中研究了该反应的机制。将肥皂放入眼睛后，前额两侧的脉搏幅度通常会短暂增加；从眼睛洗去肥皂后，同侧的反应会持续几分钟。面神经损伤会阻断损伤侧对任何一只眼睛刺激的血管反应。脸颊的脉搏幅度没有记录到一致的变化，尽管在少数受试者中观察到了反应。前额同侧的皮肤电反应通常比对侧更大；在面瘫患者中，正常神经支配侧的皮肤电反应比损伤侧更大。这些发现表明，刺激眼睛会诱发三叉神经-副交感神经血管舒张反射和局部出汗。反应的局限性分布表明，三叉神经的每个分支可能存在独立的副交感神经血管舒张反射。
