Lambertz M, Langhorst P
Institut für Physiologie, Freie Universität Berlin, Germany.
J Auton Nerv Syst. 1995 Feb 9;51(2):153-63. doi: 10.1016/0165-1838(94)00127-6.
Cardiac rhythmic discharge patterns (CRDP) of brainstem reticular neurons in anesthetized dogs were estimated by ECG-triggered post-event-time histograms (PETH). Modulations of the CRDP occur, whenever the firing levels of the neurons slowly change with periods longer than the cardiac cycle. Therefore, in the activity of one and the same neuron different types of CRDP can occur interlaced in time. 'Partial' PETHs calculated according to the discharge level of the neurons make these various CRDP obvious. On the other hand, the CRDP are not always so clear in the 'total' PETHs, taken from the continuous periods of activity. The meaning of these different CRDP for regulatory processes of the organism is discussed. We study the processing of the easily identifiable signal in neuron activity, i.e., cardiac rhythm, to illustrate how signal processing depends on the momentary activity level of the neurons which is influenced by other afferent signals and by inflows from central structures reaching the neurons.
通过心电图触发的事件后时间直方图（PETH）来估计麻醉犬脑干网状神经元的心脏节律性放电模式（CRDP）。只要神经元的放电水平随比心动周期更长的周期缓慢变化，CRDP就会发生调制。因此，在同一个神经元的活动中，不同类型的CRDP可能会在时间上交错出现。根据神经元的放电水平计算的“部分”PETH使这些不同的CRDP变得明显。另一方面，从连续活动期获取的“总”PETH中的CRDP并不总是那么清晰。讨论了这些不同的CRDP对机体调节过程的意义。我们研究神经元活动中易于识别的信号即心脏节律的处理过程，以说明信号处理如何取决于受其他传入信号和来自到达神经元的中枢结构的输入影响的神经元的瞬时活动水平。
