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牛瘟病毒诱导家兔产生的自身免疫。

Autoimmunity induced in rabbits by rinderpest virus.

作者信息

Fukuda A, Yamanouchi K

出版信息

Infect Immun. 1976 May;13(5):1449-53. doi: 10.1128/iai.13.5.1449-1453.1976.

Abstract

During rinderpest virus infection in rabbits, 19S cold hemagglutinating antibody against rabbit erythrocytes and 7S anti-nuclear antibody, which reacts with the nuclei and/or the nuclear membranes in immunofluorescent staining, were demonstrated. Virus infection that affected the thymus-dependent immune functions was speculated to act as a trigger for the production of these two autoantibodies.

摘要

在兔感染牛瘟病毒期间,发现了针对兔红细胞的19S冷血凝抗体以及在免疫荧光染色中与细胞核和/或核膜发生反应的7S抗核抗体。据推测,影响胸腺依赖性免疫功能的病毒感染是这两种自身抗体产生的触发因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de46/420779/f49afdabaa16/iai00221-0152-a.jpg

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