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1
Salmonellosis in mice: immunization experiments with salmonella-escherichia coli hybrids.小鼠沙门氏菌病：沙门氏菌-大肠杆菌杂交种的免疫实验
Infect Immun. 1976 May;13(5):1517-8. doi: 10.1128/iai.13.5.1517-1518.1976.
2
Salmonella typhimurium infection in calves: protection and survival of virulent challenge bacteria after immunization with live or inactivated vaccines.犊牛鼠伤寒沙门氏菌感染：用活疫苗或灭活疫苗免疫后强毒攻击菌的保护作用和存活情况。
Infect Immun. 1983 Aug;41(2):742-50. doi: 10.1128/iai.41.2.742-750.1983.
3
Compared efficiency of a killed vaccine of Salmonella typhimurium, a live vaccine and an antigenic fraction in oral immunization of mice.比较鼠伤寒沙门氏菌灭活疫苗、活疫苗及抗原组分对小鼠口服免疫的效果。
Dev Biol Stand. 1976;33:118-23.
4
Evaluation of two Salmonella typhimurium hybrids as challenge organisms in a system for the assay of typhoid vaccines.评估两种鼠伤寒沙门氏菌杂交菌株作为伤寒疫苗检测系统中的攻击用生物体。
Infect Immun. 1982 Oct;38(1):201-5. doi: 10.1128/iai.38.1.201-205.1982.
5
Oral immunization of mice with killed Salmonella typhimurium vaccine.用灭活的鼠伤寒沙门氏菌疫苗对小鼠进行口服免疫。
Infect Immun. 1972 Jul;6(1):58-61. doi: 10.1128/iai.6.1.58-61.1972.
6
An enterobacterial common antigen mutant of Salmonella enterica serovar Typhimurium as a vaccine candidate.鼠伤寒沙门氏菌的一种肠杆菌共同抗原突变体作为候选疫苗。
Int J Med Microbiol. 2015 Sep;305(6):511-22. doi: 10.1016/j.ijmm.2015.05.004. Epub 2015 Jun 1.
7
Combined vaccine regimen based on parenteral priming with a DNA vaccine and administration of an oral booster consisting of a recombinant Salmonella enterica serovar Typhimurium vaccine strain for immunization against infection with human-derived enterotoxigenic Escherichia coli strains.基于用DNA疫苗进行肠胃外初免以及给予由重组鼠伤寒沙门氏菌疫苗株组成的口服加强剂的联合疫苗方案，用于免疫预防人源产肠毒素大肠杆菌菌株的感染。
Infect Immun. 2004 Nov;72(11):6480-91. doi: 10.1128/IAI.72.11.6480-6491.2004.
8
Salmonella typhimurium infection in calves: cell-mediated and humoral immune reactions before and after challenge with live virulent bacteria in calves given live or inactivated vaccines.犊牛鼠伤寒沙门氏菌感染：给犊牛接种活疫苗或灭活疫苗后，用活的强毒细菌攻击前后的细胞介导免疫和体液免疫反应
Infect Immun. 1983 Aug;41(2):751-7. doi: 10.1128/iai.41.2.751-757.1983.
9
Protection of mice against Salmonella typhimurium with an O-specific polysaccharide-protein conjugate vaccine.用O-特异性多糖-蛋白质结合疫苗保护小鼠免受鼠伤寒沙门氏菌感染。
Infect Immun. 1992 Nov;60(11):4679-86. doi: 10.1128/iai.60.11.4679-4686.1992.
10
Protection against oral challenge three months after i.v. immunization of BALB/c mice with live Aro Salmonella typhimurium and Salmonella enteritidis vaccines is serotype (species)-dependent and only partially determined by the main LPS O antigen.用活的鼠伤寒沙门氏菌Aro疫苗和肠炎沙门氏菌疫苗对BALB/c小鼠进行静脉免疫三个月后，对口服攻击的保护作用是血清型（种）依赖性的，并且仅部分由主要的LPS O抗原决定。
Vaccine. 1996 Mar;14(4):251-9. doi: 10.1016/0264-410x(95)00249-z.

引用本文的文献

1
Salmonellosis in mice: studies on oral immunization with live avirulent vaccines.小鼠沙门氏菌病：关于用减毒活疫苗进行口服免疫的研究。
Med Microbiol Immunol. 1980;168(2):119-28. doi: 10.1007/BF02121760.
2
Clonal analysis of primary B cells responsive to the pathogenic bacterium Salmonella typhimurium.对致病性鼠伤寒沙门氏菌有反应的原发性B细胞的克隆分析。
J Exp Med. 1987 Feb 1;165(2):340-58. doi: 10.1084/jem.165.2.340.
3
Mouse protective capabilities of Escherichia coli hybrids expressing Salmonella typhi antigens.表达伤寒沙门氏菌抗原的大肠杆菌杂交体的小鼠保护能力。
Infect Immun. 1979 Apr;24(1):90-3. doi: 10.1128/iai.24.1.90-93.1979.
4
Intestinal and serum antibody responses in mice after oral immunization with Salmonella, Escherichia coli, and Salmonella-Escherichia coli hybrid strains.用沙门氏菌、大肠杆菌及沙门氏菌-大肠杆菌杂交菌株对小鼠进行口服免疫后，小鼠肠道及血清的抗体反应
Infect Immun. 1979 Jul;25(1):27-33. doi: 10.1128/iai.25.1.27-33.1979.
5
Effectiveness of parenteral and oral typhoid vaccination in mice challenged with a Salmonella typhi-Salmonella typhimurium hybrid.经伤寒杆菌-鼠伤寒杆菌杂交菌株攻击的小鼠中，肠胃外和口服伤寒疫苗接种的有效性。
Infect Immun. 1977 Mar;15(3):997-8. doi: 10.1128/iai.15.3.997-998.1977.

本文引用的文献

1
Mechanisms of acquired resistance in mouse typhoid.小鼠伤寒获得性耐药机制。
J Exp Med. 1966 Oct 1;124(4):585-600. doi: 10.1084/jem.124.4.585.
2
Immunity in experimental salmonellosis. 3. Comparative immunization with viable and heat-inactivated cells of Salmonella typhimurium.实验性沙门氏菌病中的免疫。3. 用鼠伤寒沙门氏菌的活细胞和热灭活细胞进行的比较免疫接种。
Infect Immun. 1972 May;5(5):792-7. doi: 10.1128/iai.5.5.792-797.1972.
3
Delayed hypersensitivity and arthus reactivity in relation to host resistance in salmonella-infected mice.沙门氏菌感染小鼠中迟发型超敏反应和阿瑟斯反应与宿主抵抗力的关系
J Immunol. 1968 Nov;101(5):830-45.
4
Assay of typhoid vaccines with Salmonella typhosa-Salmonella typhimurium hybrids.用伤寒沙门氏菌-鼠伤寒沙门氏菌杂交菌株检测伤寒疫苗
Infect Immun. 1973 Jan;7(1):5-8. doi: 10.1128/iai.7.1.5-8.1973.
5
Genetic transfer of Salmonella O antigens to Escherichia coli O8.沙门氏菌O抗原向大肠杆菌O8的基因转移。
J Gen Microbiol. 1976 Feb;92(2):311-24. doi: 10.1099/00221287-92-2-311.

小鼠沙门氏菌病：沙门氏菌-大肠杆菌杂交种的免疫实验

Salmonellosis in mice: immunization experiments with salmonella-escherichia coli hybrids.

作者信息

Kiefer W, Gransow P, Schmidt G, Westphal O

出版信息

Infect Immun. 1976 May;13(5):1517-8. doi: 10.1128/iai.13.5.1517-1518.1976.

DOI:10.1128/iai.13.5.1517-1518.1976
PMID:773838
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC420790/
Abstract

Mice vaccinated with Escherichia coli hybrids experesing Salmonella O antigens were protected against lethal challenge doses of Salmonella strains. Counts of challenge bacteria in mouse organs revealed that a live hybrid vaccine was slightly more efficient than an acetone-killed vaccine.

摘要

用表达沙门氏菌O抗原的大肠杆菌杂交体免疫的小鼠对致死剂量的沙门氏菌菌株攻击具有抵抗力。对小鼠器官中攻击细菌的计数显示，活杂交疫苗比丙酮灭活疫苗的效率略高。