实验性沙门氏菌病中的免疫。3. 用鼠伤寒沙门氏菌的活细胞和热灭活细胞进行的比较免疫接种。
Immunity in experimental salmonellosis. 3. Comparative immunization with viable and heat-inactivated cells of Salmonella typhimurium.
作者信息
Germanier R
出版信息
Infect Immun. 1972 May;5(5):792-7. doi: 10.1128/iai.5.5.792-797.1972.
Abstract
Vaccination with viable cells of an avirulent Salmonella typhimurium galE mutant provides mice with solid specific immunity against subsequent infection with a virulent smooth strain. Such a live vaccine is markedly more potent than one prepared from inactivated cells of the virulent smooth strain. The superiority of the live vaccine is particularly well demonstrated when the oral route of application is used. The protective capacity of the galE mutant is based on its ability to synthesize complete smooth-like cell wall lipopolysaccharide in vivo.
摘要
用无毒鼠伤寒沙门氏菌galE突变株的活细胞进行疫苗接种，可使小鼠获得针对后续强毒光滑菌株感染的坚实特异性免疫力。这种活疫苗比由强毒光滑菌株的灭活细胞制备的疫苗明显更有效。当采用口服途径接种时，活疫苗的优越性尤为明显。galE突变株的保护能力基于其在体内合成完整的类似光滑型细胞壁脂多糖的能力。
相似文献
1
Immunity in experimental salmonellosis. 3. Comparative immunization with viable and heat-inactivated cells of Salmonella typhimurium.
Infect Immun. 1972 May;5(5):792-7. doi: 10.1128/iai.5.5.792-797.1972.
2
Immunity conferred by Aro- Salmonella live vaccines.
Microb Pathog. 1991 Feb;10(2):149-58. doi: 10.1016/0882-4010(91)90075-l.
3
Protection against oral challenge three months after i.v. immunization of BALB/c mice with live Aro Salmonella typhimurium and Salmonella enteritidis vaccines is serotype (species)-dependent and only partially determined by the main LPS O antigen.
Vaccine. 1996 Mar;14(4):251-9. doi: 10.1016/0264-410x(95)00249-z.
4
The effect of immunization with a rough strain of Salmonella enteritidis on the fate of Salmonella typhimurium in mice.
Aust J Exp Biol Med Sci. 1974 Oct;52(5):779-89. doi: 10.1038/icb.1974.77.
5
Mouse models for assessing the cross-protective efficacy of oral non-typhoidal Salmonella vaccine candidates harbouring in-frame deletions of the ATP-dependent protease lon and other genes.
J Med Microbiol. 2015 Mar;64(Pt 3):295-302. doi: 10.1099/jmm.0.000014. Epub 2015 Jan 14.
6
Refined live attenuated Salmonella enterica serovar Typhimurium and Enteritidis vaccines mediate homologous and heterologous serogroup protection in mice.
Infect Immun. 2015 Dec;83(12):4504-12. doi: 10.1128/IAI.00924-15. Epub 2015 Sep 8.
7
Salmonellosis in mice: studies on oral immunization with live avirulent vaccines.
Med Microbiol Immunol. 1980;168(2):119-28. doi: 10.1007/BF02121760.
8
9
Immunity induced by live attenuated Salmonella vaccines.
Res Microbiol. 1990 Sep-Oct;141(7-8):757-64. doi: 10.1016/0923-2508(90)90107-2.
引用本文的文献
1
Attenuated Serovar Typhimurium, Strain NC983, Is Immunogenic, and Protective against Virulent Typhimurium Challenges in Mice.
Vaccines (Basel). 2020 Nov 3;8(4):646. doi: 10.3390/vaccines8040646.
2
In vivo activation of dendritic cells and T cells during Salmonella enterica serovar Typhimurium infection.
Infect Immun. 2001 Sep;69(9):5726-35. doi: 10.1128/IAI.69.9.5726-5735.2001.
3
Pathogenicity and protective effect of rough mutants of Salmonella species in germ-free piglets.
Infect Immun. 1997 Dec;65(12):5238-43. doi: 10.1128/iai.65.12.5238-5243.1997.
4
Effect of vaccination of hens with an avirulent strain of Salmonella typhimurium on immunity of progeny challenged with wild-Type Salmonella strains.
Infect Immun. 1996 Mar;64(3):938-44. doi: 10.1128/iai.64.3.938-944.1996.
5
Salmonella typhimurium delta aroA delta aroD mutants expressing a foreign recombinant protein induce specific major histocompatibility complex class I-restricted cytotoxic T lymphocytes in mice.
Infect Immun. 1993 Dec;61(12):5374-80. doi: 10.1128/iai.61.12.5374-5380.1993.
6
Vaccinal properties of Salmonella abortus ovis mutants for streptomycin: screening with a murine model.
Infect Immun. 1981 Nov;34(2):492-7. doi: 10.1128/iai.34.2.492-497.1981.
7
Evaluation of oral vaccination against mouse-typhoid in a new animal model.
Experientia. 1981;37(8):900-1. doi: 10.1007/BF01985703.
8
Salmonellosis in mice: studies on oral immunization with live avirulent vaccines.
Med Microbiol Immunol. 1980;168(2):119-28. doi: 10.1007/BF02121760.
9
Correlation of the duration and magnitude of protection against Salmonella infection afforded by various vaccines with antibody titers.
Infect Immun. 1980 Feb;27(2):435-43. doi: 10.1128/iai.27.2.435-443.1980.
10
The comparative histopathology of primary and secondary lesions in murine salmonellosis.
Br J Exp Pathol. 1980 Feb;61(1):76-84.
本文引用的文献
1
Immunity in Experimental Salmonellosis I. Protection Induced by Rough Mutants of Salmonella typhimurium.
Infect Immun. 1970 Sep;2(3):309-15. doi: 10.1128/iai.2.3.309-315.1970.
2
Immunity to enteric infection in mice.
Infect Immun. 1970 Mar;1(3):243-50. doi: 10.1128/iai.1.3.243-250.1970.
3
THE BASIS FOR IMMUNITY TO MOUSE TYPHOID. I. THE CARRIER STATE.
Aust J Exp Biol Med Sci. 1964 Apr;42:215-28. doi: 10.1038/icb.1964.23.
4
BASIS FOR IMMUNITY TO TYPHOID IN MICE AND THE QUESTION OF "CELLULAR IMMUNITY".
Bacteriol Rev. 1963 Dec;27(4):391-404. doi: 10.1128/br.27.4.391-404.1963.
5
Passive transfer of immunity to typhoid by macrophages.
J Bacteriol. 1962 Sep;84(3):500-7. doi: 10.1128/jb.84.3.500-507.1962.
6
The effect of the intestinal flora on the growth rate of mice, and on their susceptibility to experimental infections.
J Exp Med. 1960 Mar 1;111(3):407-17. doi: 10.1084/jem.111.3.407.
7
Resistance to reinfection in experimental mouse typhoid.
J Hyg (Lond). 1957 Sep;55(3):334-43. doi: 10.1017/s0022172400037244.
8
Host-parasite relations in mouse typhoid.
J Exp Med. 1966 Oct 1;124(4):573-83. doi: 10.1084/jem.124.4.573.
9
Two types of immunity in experimental typhoid; "cellular immunity" and "humoral immunity".
Keio J Med. 1965 Jun;14(2):45-61. doi: 10.2302/kjm.14.45.
10
Effect of specific immune mouse serum on the growth of Salmonella enteritidis in mice preimmunized with living or ethyl alcohol-killed vaccines.
J Bacteriol. 1969 Feb;97(2):676-83. doi: 10.1128/jb.97.2.676-683.1969.
Zotero 插件