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泽氏巴豆:精油对啮齿动物中枢神经系统可能产生的影响

Croton zehntneri: possible central nervous system effects of the essential oil in rodents.

作者信息

Batatinha M J, de Souza-Spinosa H, Bernardi M M

机构信息

Department of Pathology, Faculty of Veterinary Medicine and Zootechnique, University of São Paulo, Brazil.

出版信息

J Ethnopharmacol. 1995 Jan;45(1):53-7. doi: 10.1016/0378-8741(94)01195-6.

DOI:10.1016/0378-8741(94)01195-6
PMID:7739227
Abstract

The effects of essential oil of Croton zehntneri (Euphorbiaceae), orally administered were studied on behavioral parameters using rats and mice. The oil suspension did not modify pentobarbital induced-hypnosis, stereotypic behavior, catalepsy and amphetamine-induced hypermotility. The open-field behaviors were decreased and the minimal convulsant dose of pentylenetetrazole was increased.

摘要

研究了口服巴豆(大戟科)精油对大鼠和小鼠行为参数的影响。油悬液不改变戊巴比妥诱导的催眠、刻板行为、僵住症和苯丙胺诱导的运动亢进。旷场行为减少,戊四氮的最小惊厥剂量增加。

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