Sverdlova A N, Agbenoko K, Mazenko I V, Iaglova L G, Egorov N S
Mol Gen Mikrobiol Virusol. 1994 Nov-Dec(6):17-22.
The ionophoretic macrotetrolide antibiotics selective to monovalent cations K+ and mainly to NH4+ were determined during the lag period of culture growth. At this stage the cells contain the maximal amounts of Na+ and K+. Macrotetrolides, whose selectivity to Na+ and K+ varies, can regulate the intracellular content of these cations by participating in the cation transport. The authors propose that the cells possess furosemide sensitivity and K+/Na+ ATPase transport systems.
在培养生长的延迟期测定了对单价阳离子K⁺有选择性且主要对NH₄⁺有选择性的离子载体大环四萜类抗生素。在此阶段，细胞含有最大量的Na⁺和K⁺。对Na⁺和K⁺选择性不同的大环四萜类抗生素可通过参与阳离子转运来调节这些阳离子的细胞内含量。作者提出细胞具有速尿敏感性和K⁺/Na⁺ATP酶转运系统。
