Sverdlova A N, Agbenoko K, Iaglova L G, Egorov N S
Antibiot Khimioter. 1992 Jan;37(1):8-11.
The dynamics of calcium accumulation by cells in batch cultures and by washed cells was defined with a radiotracer procedure for Streptomyces chrysomallus var. macrotetrolidi producing ionophore macrotetrolide antibiotics. It was shown that macrotetrolides added to the cultivation medium could regulate intracellular contents of calcium by participating in cation transport. Moreover, possible functioning of a Ca-ATPase system for the calcium active transport in the streptomycete cells was demonstrated.