Niezychowska K, Zawádzki J, Wejman J
Department of Pathomorphology, Postgraduate Medical Center, Warszawa.
Pol J Pathol. 1997;48(3):205-7.
A case of primary malignant melanoma of the esophagus has been reported. This rare entity accounts for less than 0.2% of all esophageal neoplasms. A polypoid, deep blue and tough tumour was present on endoscopic examination during which a few samples were taken. Microscopically melanotic tissue occupied the whole submucosa and scanty deposits of melanin pigment were dispersed. Positive immunohistochemical stain with HMB-45 antibody confirmed the diagnosis of malignant melanoma. The patient was admitted to the Oncological Center for resection of the tumour, which is the treatment of choice in such cases.
已报告一例原发性食管恶性黑色素瘤。这种罕见的肿瘤在所有食管肿瘤中占比不到0.2%。内镜检查时发现一个息肉样、深蓝色且质地坚韧的肿瘤，期间采集了一些样本。显微镜下可见黑素组织占据整个黏膜下层，并有少量黑色素沉着散在分布。HMB - 45抗体免疫组化染色阳性确诊为恶性黑色素瘤。患者被收治入肿瘤中心进行肿瘤切除，这是此类病例的首选治疗方法。
