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原发性食管恶性黑色素瘤。病例报告。

Primary malignant melanoma of the esophagus. A case report.

作者信息

Niezychowska K, Zawádzki J, Wejman J

机构信息

Department of Pathomorphology, Postgraduate Medical Center, Warszawa.

出版信息

Pol J Pathol. 1997;48(3):205-7.

PMID:9401415
Abstract

A case of primary malignant melanoma of the esophagus has been reported. This rare entity accounts for less than 0.2% of all esophageal neoplasms. A polypoid, deep blue and tough tumour was present on endoscopic examination during which a few samples were taken. Microscopically melanotic tissue occupied the whole submucosa and scanty deposits of melanin pigment were dispersed. Positive immunohistochemical stain with HMB-45 antibody confirmed the diagnosis of malignant melanoma. The patient was admitted to the Oncological Center for resection of the tumour, which is the treatment of choice in such cases.

摘要

已报告一例原发性食管恶性黑色素瘤。这种罕见的肿瘤在所有食管肿瘤中占比不到0.2%。内镜检查时发现一个息肉样、深蓝色且质地坚韧的肿瘤,期间采集了一些样本。显微镜下可见黑素组织占据整个黏膜下层,并有少量黑色素沉着散在分布。HMB - 45抗体免疫组化染色阳性确诊为恶性黑色素瘤。患者被收治入肿瘤中心进行肿瘤切除,这是此类病例的首选治疗方法。

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