Ruckdeschel J C
H. Lee Moffitt Cancer Center and Research Institute, University of South Florida, Tampa 33612-9497, USA.
Semin Oncol. 1995 Apr;22(2 Suppl 3):58-63.
Malignant pleural effusions are a common complication of advanced cancer, particularly breast and lung cancers. Clinical algorithms for the diagnosis and management of malignant pleural effusions form a framework for the cost-effective provision of meaningful palliation. When the entire episode of care is considered, the optimal therapy for malignant pleural effusions appears to be tube thoracostomy followed by intrapleural bleomycin. Alternative strategies for the delivery of intrapleural therapy (eg, soft catheters) and new intrapleural agents currently are being compared with standard therapy.
恶性胸腔积液是晚期癌症常见的并发症，尤其是乳腺癌和肺癌。恶性胸腔积液诊断和管理的临床算法构成了提供具有成本效益的有效姑息治疗的框架。当考虑整个治疗过程时，恶性胸腔积液的最佳治疗方法似乎是胸腔闭式引流术，随后进行胸膜腔内注射博来霉素。目前正在将胸膜腔内治疗的替代策略（如软导管）和新的胸膜腔内药物与标准治疗进行比较。
