Mori G, Fabra A, Castro S, Rivarola V, Giordano W, Balegno H
Facultad de Ciencias Exactas, Físico-Químicas y Naturales, Universidad Nacional de Río Cuarto, Córdoba, Argentina.
Toxicology. 1995 Apr 12;98(1-3):23-9. doi: 10.1016/0300-483x(95)02952-5.
We had previously demonstrated that 1 mM 2,4-D inhibited cell growth, nucleic acid synthesis and protein synthesis (at the ribosomal level) of Azospirillum brasilense. These alterations were prevented by the presence of polyamines in the culture medium. On the other hand, polyamines did not affect the 2,4-D uptake. In this paper we demonstrate that 2,4-D alters the metabolism of polyamines and increases their uptake.
我们之前已经证明，1 mM 2,4-二氯苯氧乙酸（2,4-D）会抑制巴西固氮螺菌的细胞生长、核酸合成以及蛋白质合成（在核糖体水平）。培养基中多胺的存在可防止这些变化。另一方面，多胺并不影响2,4-D的摄取。在本文中，我们证明2,4-D会改变多胺的代谢并增加其摄取。
