Aliev M N, Rzaev R N, Mamedbeĭli T N, Aliev A N
Zh Nevrol Psikhiatr Im S S Korsakova. 1994;94(6):58-60.
Activated lipid peroxidation observed in brain homogenates in experimental choreoid hyperkinesis and bemegride epilepsy can be arrested by antioxidant pretreatment. The same is true for parkinsonian and "malignant locomotion" syndromes provoked by intrastriatal pro-oxidant (oxidized oleinic acid) microinjection and systemic administration of haloperidol. Experimental therapy of choreoid hyperkinesis with GABA-positive and dopamine-blocking drugs alone proved ineffective. The effect was achieved at combined application of antioxidant and GABA-positive drugs.
在实验性脉络膜多动症和贝美格癫痫的脑匀浆中观察到的活性脂质过氧化可通过抗氧化剂预处理来阻止。纹状体内注射促氧化剂（氧化油酸）和全身给予氟哌啶醇引发的帕金森综合征和“恶性运动”综合征也是如此。单独使用GABA阳性和多巴胺阻断药物对脉络膜多动症进行实验性治疗被证明是无效的。抗氧化剂和GABA阳性药物联合应用可取得疗效。
