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异基因骨髓移植后乙肝再激活:病例报告及文献综述

Hepatitis B reactivation following allogeneic bone marrow transplantation: case report and review of the literature.

作者信息

Martin B A, Rowe J M, Kouides P A, DiPersio J F

机构信息

Department of Medicine, University of Rochester School of Medicine.

出版信息

Bone Marrow Transplant. 1995 Jan;15(1):145-8.

PMID:7742749
Abstract

A case of hepatitis B reactivation following allogeneic bone marrow transplantation for acute myelogenous leukemia is reported. The presence of hepatitis B surface antibody prior to transplantation indicated previous infection with hepatitis B. The presence of hepatitis B surface antigen was first detected 21 months after transplantation. Testing for hepatitis B reactivation was prompted by the development of acute hepatitis B in the patient's spouse. Screening for hepatitis B infection may be helpful when abnormal liver function tests develop after bone marrow transplantation.

摘要

报告了1例急性髓性白血病异基因骨髓移植后乙型肝炎再激活的病例。移植前存在乙型肝炎表面抗体表明既往感染过乙型肝炎。移植后21个月首次检测到乙型肝炎表面抗原。患者配偶发生急性乙型肝炎促使对乙型肝炎再激活进行检测。骨髓移植后出现肝功能检查异常时,筛查乙型肝炎感染可能会有帮助。

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