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局部用利多卡因能否降低对足跟采血的行为反应?

Can topical lignocaine reduce behavioural response to heel prick?

作者信息

Rushforth J A, Griffiths G, Thorpe H, Levene M I

机构信息

Academic Department of Paediatrics, General Infirmary at Leeds.

出版信息

Arch Dis Child Fetal Neonatal Ed. 1995 Jan;72(1):F49-51. doi: 10.1136/fn.72.1.f49.

DOI:10.1136/fn.72.1.f49
PMID:7743286
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2528406/
Abstract

In a randomised, double blind, controlled study the ability of 5% lignocaine ointment to reduce the behavioural response to heel lance in 30 healthy neonates was assessed. Five per cent lignocaine ointment applied to the heel under an occlusive dressing for one hour before heel prick did not reduce the infants' behavioural response to the heel prick procedure.

摘要

在一项随机、双盲、对照研究中,评估了5%利多卡因软膏对30名健康新生儿足跟采血行为反应的缓解能力。在足跟采血前1小时,将5%利多卡因软膏涂于足跟并覆盖封闭敷料,并未减轻婴儿对足跟采血操作的行为反应。

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Can topical lignocaine reduce behavioural response to heel prick?局部用利多卡因能否降低对足跟采血的行为反应?
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Analgesic effect of lidocaine ointment on intact skin in neonates.利多卡因软膏对新生儿完整皮肤的镇痛作用。
Acta Paediatr. 1993 Sep;82(9):791. doi: 10.1111/j.1651-2227.1993.tb12560.x.
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Behavioural response to pain in healthy neonates.健康新生儿对疼痛的行为反应。
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Methemoglobinemia associated with a prilocaine-lidocaine cream and trimetoprim-sulphamethoxazole. A case report.
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7
Plasma concentrations of prilocaine and lidocaine and methaemoglobin formation in infants after epicutaneous application of a 5% lidocaine-prilocaine (EMLA).5%利多卡因-丙胺卡因(复方利多卡因乳膏)经皮应用于婴儿后丙胺卡因、利多卡因的血浆浓度及高铁血红蛋白的形成
Acta Anaesthesiol Scand. 1987 Oct;31(7):624-8. doi: 10.1111/j.1399-6576.1987.tb02633.x.
8
Inverse relationship between age-dependent erythrocyte activity of methaemoglobin reductase and prilocaine-induced methaemoglobinaemia during infancy.婴儿期高铁血红蛋白还原酶的年龄依赖性红细胞活性与丙胺卡因诱导的高铁血红蛋白血症之间的负相关关系。
Br J Anaesth. 1990 Jan;64(1):72-6. doi: 10.1093/bja/64.1.72.