Drake D B, Oishi S N
Department of Surgery, University of Kentucky Chandler Medical Center, Lexington, USA.
Clin Plast Surg. 1995 Jan;22(1):31-7.
Adjunctive radiation and chemotherapy have evolved to increase the survival rates and disease-free intervals that can be accomplished with surgical resection. We have reviewed the salient effects these agents have on wound healing. Further investigations into the specific wound-healing deficits caused by these agents and the development of interventional therapies will enable us to manipulate the wound milieu in order to accomplish the goal of oncologic cytoreductive therapy without detrimental effects on wound healing.
辅助放疗和化疗已经发展到能够提高通过手术切除所能达到的生存率和无病生存期。我们回顾了这些药物对伤口愈合的显著影响。对这些药物引起的特定伤口愈合缺陷进行进一步研究以及开发介入治疗方法，将使我们能够调控伤口环境，从而实现肿瘤细胞减灭治疗的目标，同时又不对伤口愈合产生不利影响。
