Borstlap M, Zant J L, van Soesbergen R M, van der Korst J K
Jan van Breemen Institute, Centre for Rheumatology and Rehabilitation, Amsterdam, The Netherlands.
Clin Rheumatol. 1995 Jan;14(1):15-20. doi: 10.1007/BF02208079.
Three experimental questionnaires were compared with the Influence of Rheumatic Diseases on Health and Lifestyle (IRGL) questionnaire, a Dutch version of the Arthritis Impact Measurement Scales. Sixty-two patients with osteoarthritis (OA) and 35 patients with rheumatoid arthritis (RA), all of whom underwent hip arthroplasty, completed the study. Results showed that visual analogue scales for pain, stiffness, fatigue, and anxiety were strongly correlated with a number of the IRGL scales. Patient preference scales were sensitive to change and provided additional information on aspects of the patients' quality of life (QOL) that were felt to be important by the patients themselves. The questionnaire on performance in various roles in life was insensitive to change. In existing questionnaires, there is an attempt to represent the concept of QOL in terms of its most important aspects. Such realizations of the concept of QOL are not entirely suitable for application in clinical trials. The IRGL is overly complex, and its sometimes comprehensive scales do not deal with the possible effects of treatment. Neither of these properties is conducive to sensitivity to change. Visual analogue scales reduce the complexity. A simpler representation of QOL that can evaluate aspects relevant to treatment is recommended.
将三份实验性问卷与《风湿性疾病对健康和生活方式的影响》(IRGL)问卷进行了比较,后者是荷兰版的关节炎影响测量量表。62例骨关节炎(OA)患者和35例类风湿关节炎(RA)患者均接受了髋关节置换术,完成了该研究。结果显示,疼痛、僵硬、疲劳和焦虑的视觉模拟量表与多个IRGL量表密切相关。患者偏好量表对变化敏感,并提供了关于患者生活质量(QOL)方面的额外信息,这些方面是患者自身认为重要的。关于在生活中各种角色表现的问卷对变化不敏感。在现有的问卷中,试图从最重要的方面来体现生活质量的概念。这种生活质量概念的实现并不完全适用于临床试验。IRGL过于复杂,其有时全面的量表并未涉及治疗的可能效果。这两个特性都不利于对变化的敏感性。视觉模拟量表降低了复杂性。建议采用一种更简单的生活质量表示方法,能够评估与治疗相关的方面。