Puri P, Ninan G K, Surana R
Children's Research Centre, Our Lady's Hospital for Sick Children, Crumlin, Dublin, Ireland.
Eur Urol. 1995;27(1):71-5. doi: 10.1159/000475128.
Subureteric Teflon injection (STING) has been successfully used by several investigators for treating vesicoureteric reflux (VUR) in children. This multicentre European survey reviews the results of STING in 6,216 ureters. Twenty-two paediatric surgeons/urologists from 18 centres in Europe answered an enquiry regarding their experience with STING in the treatment of VUR. 6,216 refluxing ureters were injected with Polytef paste in 4,166 children during 1984-1990. There were 975 boys and 3,191 girls. Their ages ranged from 2 months to 14 years (mean 5.1 years). The reflux was grade I in 4.4% of ureters, grade II in 36.1%, grade III in 40.2%, and grades IV and V in 19.3% of ureters. All patients were followed up for periods ranging from 3 months to 81/2 years and 90% were followed up for more than 2 years. 76.3% of all ureters stopped refluxing after a single injection of Teflon paste, cure rate increased to 84.9% after a second injection. A further 10.2% of refluxing ureters showed significant improvement in the grade of reflux after a single injection and needed no further treatment. 1.3% of ureters were cured after a third or fourth injection. Failure to correct or improve VUR was seen in 224 ureters (3.6%), necessitating reimplantation. Twenty ureters (0.32%) developed vesicoureteric junction obstruction following STING and these were reimplanted without difficulty. Results of this multicentre survey confirm that STING is an effective day care procedure for treatment of all grades of VUR. 95% of all ureters were cured or showed significant improvement after two injections of Teflon paste.(ABSTRACT TRUNCATED AT 250 WORDS)
输尿管下聚四氟乙烯注射（STING）已被一些研究者成功用于治疗儿童膀胱输尿管反流（VUR）。这项欧洲多中心调查回顾了6216条输尿管的STING治疗结果。来自欧洲18个中心的22名儿科外科医生/泌尿科医生回答了关于他们使用STING治疗VUR的经验的询问。在1984年至1990年期间，对4166名儿童的6216条反流输尿管注射了聚四氟乙烯糊剂。其中有975名男孩和3191名女孩。他们的年龄从2个月到14岁不等（平均5.1岁）。输尿管反流分级为I级的占4.4%，II级的占36.1%，III级的占40.2%，IV级和V级的占19.3%。所有患者的随访时间从3个月到8年半不等，90%的患者随访时间超过2年。单次注射聚四氟乙烯糊剂后，76.3%的输尿管停止反流，第二次注射后治愈率提高到84.9%。另外有10.2%的反流输尿管在单次注射后反流分级有显著改善，无需进一步治疗。1.3%的输尿管在第三次或第四次注射后治愈。224条输尿管（3.6%）未能纠正或改善VUR，需要重新植入。20条输尿管（0.32%）在STING后发生膀胱输尿管连接部梗阻，这些输尿管顺利进行了重新植入。这项多中心调查结果证实，STING是治疗各级VUR的一种有效的日间护理程序。两次注射聚四氟乙烯糊剂后，95%的输尿管治愈或有显著改善。（摘要截选至250词）
