Eanes R
Thomas Jefferson University Hospital, Philadelphia, USA.
J Obstet Gynecol Neonatal Nurs. 1995 Feb;24(2):119-24. doi: 10.1111/j.1552-6909.1995.tb02452.x.
Studies in preterm animals and humans have shown that liquid ventilation is a potential alternative mode of support for neonates with respiratory failure. Perfluorochemicals have a high solubility for respiratory gases and can be instilled in the lung using lower pressures than with gas ventilation. Other potential advantages of liquid ventilation include decreased alveolar surface tension, improved pulmonary mechanics, alveolar recruitment, and the removal of pulmonary debris. This article describes in detail what liquid ventilation is, compares the physiologic effects of liquid ventilation to gas ventilation, and presents the nursing implications of this technique. A review of the recent literature on the subject is presented, including reports of laboratory and clinical experience with liquid ventilation.
对早产动物和人类的研究表明，液体通气是呼吸衰竭新生儿一种潜在的替代支持模式。全氟化合物对呼吸气体具有高溶解度，并且可以使用比气体通气更低的压力注入肺内。液体通气的其他潜在优势包括降低肺泡表面张力、改善肺力学、肺泡复张以及清除肺内碎屑。本文详细描述了什么是液体通气，比较了液体通气与气体通气的生理效应，并介绍了该技术的护理要点。本文还对该主题的近期文献进行了综述，包括液体通气的实验室和临床经验报告。
