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[科学营养研究成果在临床实践中的应用]

[The use of results of scientific nutrition research in clinical practice].

作者信息

Bíró G

机构信息

Országos Elelmezés- és Táplálkozástudományi Intézet, Budapest.

出版信息

Orv Hetil. 1995 May 7;136(19):979-83.

PMID:7746662
Abstract

Author surveys clinically relevant results of recent years' nutritional researches. More and more details of the etiological bases of the diet-disease relation are revealed by molecular biology, e.g. the genetic background of link between fat intake and cardiovascular diseases, the metabolism of fatty acids. The results may be used in the implementation of balanced nutrition serving for prevention and in the elaboration of recommended levels of nutrient intake. Proper nutrition starts already in the fetal life: deficient nutrient supply of the mother means a risk factor to chronic, noncommunicable diseases of adulthood. Different nutrients, components in food might be especially favourable to health status, this phenomenon is indicated in English written scientific literature by the word "nutraceutical" (in Japan "functional foods"). In the year of 1994, the buzz word of nutrition was: antioxidant. The mechanism of the development of oxidative stress, its inhibition by antioxidative agents in food and the use of it in the prevention of malignant tumors (cancers), cardiovascular diseases, cataracts and other degenerative processes of old age, were studied comprehensively. The importance of obesity, fat intake in the risk of chronic diseases constitutes a separate group of problems. Nutrition is also an important factor in the care of HIV/AIDS patients and in the inhibition of the transfer of HIV-1 between mother and fetus.

摘要

作者综述了近年来营养研究的临床相关结果。分子生物学揭示了饮食与疾病关系病因基础的越来越多细节,例如脂肪摄入与心血管疾病之间联系的遗传背景、脂肪酸的代谢。这些结果可用于实施预防的均衡营养以及制定营养素推荐摄入量。合理营养在胎儿期就已开始:母亲营养供应不足是成年期慢性非传染性疾病的一个风险因素。不同营养素、食物中的成分可能对健康状况特别有益,英文科学文献中用“营养保健品”(在日本为“功能性食品”)一词来表示这种现象。1994年,营养领域的热门词汇是:抗氧化剂。人们全面研究了氧化应激的发生机制、食物中抗氧化剂对其的抑制作用以及在预防恶性肿瘤(癌症)、心血管疾病、白内障和其他老年退行性病变中的应用。肥胖、脂肪摄入在慢性病风险中的重要性构成了另一类问题。营养也是护理艾滋病毒/艾滋病患者以及抑制艾滋病毒-1在母婴之间传播的一个重要因素。

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