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复发性化脓性胆管炎的外科治疗

Surgical treatment of recurrent pyogenic cholangitis.

作者信息

Stain S C, Incarbone R, Guthrie C R, Ralls P W, Rivera-Lara S, Parekh D, Yellin A E

机构信息

Department of Surgery, University of Southern California School of Medicine, Los Angeles, USA.

出版信息

Arch Surg. 1995 May;130(5):527-32; discussion 532-3. doi: 10.1001/archsurg.1995.01430050077013.

Abstract

OBJECTIVE

To examine the evolving operative strategies in the treatment of recurrent pyogenic cholangitis (RPC).

DESIGN

Case series of patients with RPC treated surgically at the Los Angeles County-University of Southern California Medical Center between 1980 and 1994.

SETTING

Public teaching hospital.

PATIENTS

Twenty patients with RPC were studied. The clinical diagnosis of RPC was made in patients with a syndrome of chronic intermittent attacks of biliary sepsis associated with intrahepatic biliary strictures and intrahepatic stones.

MAIN OUTCOME MEASURE

The need for repeated biliary intervention after surgical treatment of RPC.

RESULTS

Four patients had a hepatic lobectomy without biliary enteric bypass. One patient had an uneventful course. Three patients had postoperative biliary sepsis, and one of these patients died. A hepaticojejunostomy without a cutaneous stoma was performed in eight patients. Five (63%) of these eight required repeated operation for biliary sepsis 1 to 4 years after surgery. In eight patients, a Roux-en-Y hepaticojejunostomy was performed after attempted clearance of intrahepatic stones with construction of a temporary cutaneous stoma. Postoperatively, these eight patients had 16 transstomal endoscopic cholangiograms (mean follow-up, 10 months). Stones proximal to intrahepatic strictures were identified in seven endoscopic sessions in five of these patients (63%). The stones were removed, and the strictures were endoscopically dilated. None required repeated biliary operation.

CONCLUSION

RPC is a progressive, lifelong disease. Construction of a hepaticojejunostomy with a cutaneous stoma allows future therapeutic intervention without the need for repeated surgery.

摘要

目的

探讨复发性化脓性胆管炎(RPC)治疗中不断演变的手术策略。

设计

1980年至1994年间在洛杉矶县-南加州大学医学中心接受手术治疗的RPC患者病例系列。

地点

公立教学医院。

患者

研究了20例RPC患者。RPC的临床诊断基于慢性间歇性胆源性败血症综合征伴肝内胆管狭窄和肝内结石的患者。

主要观察指标

RPC手术治疗后再次进行胆道干预的必要性。

结果

4例患者接受了肝叶切除术,未行胆肠吻合术。1例患者病程顺利。3例患者术后发生胆源性败血症,其中1例死亡。8例患者进行了无皮肤造口的肝空肠吻合术。这8例患者中有5例(63%)在术后1至4年因胆源性败血症需要再次手术。8例患者在尝试清除肝内结石并建立临时皮肤造口后进行了Roux-en-Y肝空肠吻合术。术后,这8例患者共进行了16次经造口内镜胆管造影(平均随访10个月)。在其中5例患者(63%)的7次内镜检查中发现了肝内狭窄近端的结石。结石被清除,狭窄通过内镜扩张。无一例需要再次进行胆道手术。

结论

RPC是一种进行性的终身疾病。构建带皮肤造口的肝空肠吻合术可在无需重复手术的情况下进行未来的治疗干预。

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