Chan C C, Roberge R G, Whitcup S M, Nussenblatt R B
Laboratory of Immunology and Clinical Branch, National Eye Institute, Bethesda, Md., USA.
Arch Ophthalmol. 1995 May;113(5):597-600. doi: 10.1001/archopht.1995.01100050065032.
To examine the relationship between visual outcome and the clinical management of patients with sympathetic ophthalmia.
Thirty-two patients with sympathetic ophthalmia who were seen at the National Eye Institute, Bethesda, Md, between 1982 and 1992, were retrospectively reviewed.
There were equal numbers of males and females. Sympathetic ophthalmia occurred after trauma in 23 patients and surgery in nine patients. Sixteen of the 32 patients had a final visual acuity of 20/40 or better; 10 patients had a visual acuity worse than 20/200. Good visual outcome was associated with early and aggressive treatment with corticosteroids, sometimes in combination with other immunosuppressive agents. Poor visual acuity was associated with glaucoma, chorioretinal scars in the macula, and persistent uncontrolled inflammation.
Prompt and aggressive use of antiinflammatory therapy can improve the visual outcome of patients with sympathetic ophthalmia.
探讨交感性眼炎患者的视觉预后与临床治疗之间的关系。
对1982年至1992年间在美国国立眼科研究所（位于马里兰州贝塞斯达）就诊的32例交感性眼炎患者进行回顾性研究。
男女患者数量相等。23例患者的交感性眼炎发生于外伤后，9例发生于手术后。32例患者中，16例最终视力达到20/40或更好；10例患者视力低于20/200。良好的视觉预后与早期积极使用皮质类固醇治疗有关，有时联合其他免疫抑制剂。视力不佳与青光眼、黄斑区脉络膜视网膜瘢痕以及持续性炎症控制不佳有关。
及时、积极地使用抗炎治疗可改善交感性眼炎患者的视觉预后。
