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交感性眼炎:现代免疫抑制疗法的视觉效果

Sympathetic ophthalmia: visual results with modern immunosuppressive therapy.

作者信息

Hakin K N, Pearson R V, Lightman S L

机构信息

Moorfields Eye Hospital, London, UK.

出版信息

Eye (Lond). 1992;6 ( Pt 5):453-5. doi: 10.1038/eye.1992.95.

Abstract

Sympathetic ophthalmia is a rare bilateral panuveitis that follows penetrating injury to one eye. The use of systemic corticosteroids has transformed the prognosis, and good acuity in the sympathizing eye can now be achieved. The use of immunosuppressive drugs, such as cyclosporin and azathioprine, in combination with the steroids, allows control of the intraocular inflammation at a much lower steroid dose, with concomitant reduction in the systemic side effects that accompany the use of systemic steroids.

摘要

交感性眼炎是一种罕见的双侧全葡萄膜炎,继发于一只眼的穿通伤。全身使用糖皮质激素改变了预后,现在患眼可以获得良好的视力。将免疫抑制药物(如环孢素和硫唑嘌呤)与糖皮质激素联合使用,能够以更低的糖皮质激素剂量控制眼内炎症,同时减少全身使用糖皮质激素所伴随的全身副作用。

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