Carter B G, Butt W W
Intensive Care Unit, Royal Children's Hospital, Victoria, Australia.
Pediatr Neurol. 1995 Jan;12(1):42-6. doi: 10.1016/0887-8994(94)00116-j.
Somatosensory evoked potentials (SEPs) were recorded from 11 patients receiving venoarterial extracorporeal membrane oxygenation (ECMO). Cortical responses recorded from the right and left hemispheres were compared to those from 2 other groups of children who were not receiving ECMO. One group consisted of 99 brain-injured patients, while the other consisted of a group of 17 neurologically normal controls. SEP responses from each hemisphere were categorized into 3 grades based on the N20 component--normal latency, abnormal (latency increased > 3 S.D.), or absent. For ECMO patients, 15% of tests disclosed a disagreement between the right and left hemispheres, while 27% of tests from the control group revealed a disagreement between the right and left hemispheres. SEPs were normal over the right hemisphere in 9 patients. Central conduction times obtained from the right and left hemispheres were similar in ECMO patients and were not different from those recorded from a group of patients suffering hypoxic-ischemic injuries and a group of normal controls who did not receive ECMO. The results of this pilot study suggest that SEPs may be employed to evaluate ECMO patients as they are in other brain-injured patients.
对11名接受静脉-动脉体外膜肺氧合（ECMO）治疗的患者记录体感诱发电位（SEP）。将左右半球记录的皮层反应与另外两组未接受ECMO治疗的儿童的反应进行比较。一组由99名脑损伤患者组成，另一组由17名神经功能正常的对照儿童组成。根据N20成分，将每个半球的SEP反应分为3个等级——潜伏期正常、异常（潜伏期增加>3个标准差）或缺失。对于接受ECMO治疗的患者，15%的测试显示左右半球之间存在差异，而对照组27%的测试显示左右半球之间存在差异。9名患者右半球的SEP正常。接受ECMO治疗的患者左右半球的中枢传导时间相似，与一组缺氧缺血性损伤患者和一组未接受ECMO治疗的正常对照记录的时间无差异。这项初步研究的结果表明，SEP可用于评估接受ECMO治疗的患者，就像用于评估其他脑损伤患者一样。
