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滴露中毒后的化学性胃食管炎、上消化道出血及胃镜检查结果

Chemical gastro-oesophagitis, upper gastrointestinal haemorrhage and gastroscopic findings following Dettol poisoning.

作者信息

Chan T Y, Sung J J, Critchley J A

机构信息

Department of Clinical Pharmacology, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories.

出版信息

Hum Exp Toxicol. 1995 Jan;14(1):18-9. doi: 10.1177/096032719501400104.

Abstract
  1. Dettol liquid (chloroxylenol 4.8%, pine oil, isopropyl alcohol), a household disinfectant, has a corrosive action on the gastrointestinal mucosa when swallowed. The incidence of upper gastrointestinal haemorrhage and gastroscopic findings following Dettol poisoning was studied in 89 patients. 2. Five patients (5.6%) developed minor haematemesis, in the form of coffee-coloured or blood-stained vomitus. One patient had a gastroscopy performed on the day after admission, showing signs of chemical burns in the oesophagus and stomach. Gastroscopy was performed in one other patient on day 11 to rule out oesophageal stricture; the patient was normal. All patients completely recovered. 3. The data from this study suggest that upper gastrointestinal haemorrhage following Dettol poisoning tends to be mild and self-limiting. Gastroscopy, which may increase the risk of aspiration in patients with impaired consciousness, is not required unless other causes of gastrointestinal bleeding are suspected.
摘要
  1. 滴露消毒液(对氯间二甲苯酚4.8%、松油、异丙醇)是一种家用消毒剂,吞咽后会对胃肠道黏膜产生腐蚀作用。对89例滴露中毒患者的上消化道出血发生率及胃镜检查结果进行了研究。2. 5例患者(5.6%)出现少量呕血,表现为咖啡色或带血的呕吐物。1例患者入院次日进行了胃镜检查,显示食管和胃有化学烧伤迹象。另1例患者在第11天进行胃镜检查以排除食管狭窄;该患者正常。所有患者均完全康复。3. 本研究数据表明,滴露中毒后的上消化道出血往往较轻且具有自限性。除非怀疑有其他胃肠道出血原因,否则对于意识障碍患者,胃镜检查可能会增加误吸风险,无需进行。

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