滴露中毒时误吸的风险：一项回顾性队列研究。

The risk of aspiration in Dettol poisoning: a retrospective cohort study.

Chan T Y, Critchley J A, Lau J T

Department of Clinical Pharmacology, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories.

Hum Exp Toxicol. 1995 Feb;14(2):190-1. doi: 10.1177/096032719501400206.

Abstract

To determine if the risk of aspiration is increased in 'Dettol' (4.8% chloroxylenol, pine oil and isopropyl alcohol) poisoning and the factors that may be responsible, a study was made of 89 patients and 89 matched control subjects with other forms of poisoning admitted to the Prince of Wales Hospital, Hong Kong. 2. Aspiration was more common in patients with Dettol poisoning (8% vs 3%, P = 0.16). There were more control subjects with drowsiness at presentation (54% vs 24%, P < 0.0001), but the use of gastric lavage (88% vs 64%, P < 0.001) and the occurrence of vomiting (62% vs 17%, P < 0.0001) were more common in patients with Dettol poisoning. 3. Our findings suggest that Dettol poisoning may be associated with an increased risk of aspiration. This increase in risk may be related to the use of gastric lavage and the common occurrence of vomiting in patients with Dettol poisoning.

摘要

为了确定滴露（含4.8%对氯间二甲苯酚、松油和异丙醇）中毒时误吸风险是否增加以及可能导致该情况的因素，对香港威尔士亲王医院收治的89例滴露中毒患者和89例匹配的其他形式中毒对照受试者进行了一项研究。2. 误吸在滴露中毒患者中更为常见（8% 对3%，P = 0.16）。就诊时对照组中嗜睡的受试者更多（54% 对24%，P < 0.0001），但洗胃的使用情况（88% 对64%，P < 0.001）以及呕吐的发生率（62% 对17%，P < 0.0001）在滴露中毒患者中更为常见。3. 我们的研究结果表明，滴露中毒可能与误吸风险增加有关。这种风险增加可能与洗胃的使用以及滴露中毒患者中呕吐的常见发生有关。