Ogasawara K, Une Y, Nakajima Y, Uchino J
First Department of Surgery, Hokkaido University School of Medicine, Sapporo, Japan.
Surg Today. 1995;25(1):43-8. doi: 10.1007/BF00309384.
The authors have developed a system to measure the volume of the liver parenchyma and tumors using computed tomographic images printed on film. The present study was carried out to clarify the usefulness of this method to assess both liver volume and the relationship between the volume increase and the functional recovery. We investigated 55 patients who underwent a hepatic resection of more than one segment. We calculated the effective resection of ratio and the liver volume increase at the 4th postoperative week to evaluate postoperative hepatic insufficiency. The liver volume increase 4 weeks after surgery correlated significantly with the effective resection ratio and also showed an inverse correlation with the severity of chronic changes in the liver. The liver volume increase also inversely correlated with the preoperative retention of indocyanine green at 15 min. Patients with postoperative hepatic insufficiency tended to show a smaller liver volume increase than expected for their resection ratio. In contrast, noncirrhotic patients had no such particular tendency. In conclusion, measurement of the liver volume using this technique appears to be a simple and useful method to evaluate liver volume after resection; as such, it may also be used to evaluate hepatic regeneration after resection.
作者开发了一种利用打印在胶片上的计算机断层扫描图像来测量肝实质和肿瘤体积的系统。本研究旨在阐明该方法在评估肝脏体积以及体积增加与功能恢复之间关系方面的实用性。我们调查了55例行超过一个肝段肝切除术的患者。我们计算了术后第4周的有效切除率和肝脏体积增加量，以评估术后肝功能不全情况。术后4周肝脏体积的增加与有效切除率显著相关，并且与肝脏慢性改变的严重程度呈负相关。肝脏体积增加也与术前15分钟吲哚菁绿潴留呈负相关。术后发生肝功能不全的患者，其肝脏体积增加往往比根据其切除率预期的要小。相比之下，非肝硬化患者没有这种特殊趋势。总之，使用该技术测量肝脏体积似乎是评估肝切除术后肝脏体积的一种简单且有用的方法；因此，它也可用于评估肝切除术后的肝再生情况。
