Yanaga K, Honda H, Ikeda Y, Nishizaki A T, Yamamoto K, Sugimachi K
Department of Surgery II, Kyushu University Faculty of Medicine, Fukuoka, Japan.
HPB Surg. 1997;10(4):195-9; discussion 199-200. doi: 10.1155/1997/34842.
The purpose of this study was to evaluate the significance of liver volumetry as a parameter for hepatic functional reserve in cirrhotic patients with hepatocellular carcinoma. Liver volume was calculated from preoperative computed tomograms of 44 cirrhotic patients who underwent elective hepatic resections for hepatocellular carcinoma. The liver volume per body weight of non-alcoholic cirrhotics was significantly smaller than that of alcoholic cirrhotics (20.9 vs. 26.7 cc/kg; p = 0.03). The values for alcoholic cirrhotics was comparable with normal values. The liver volume per body weight of the cirrhotic patients demonstrated correlation with the preoperative serum albumin (p < 0.01) and indocyanine green clearance (p = 0.02). We conclude that the determination of hepatic atrophy by volumetry can serve as a parameter for the assessment of hepatic reserve but not as a predictor of postoperative complications in elective liver surgery for cirrhotic patients.
本研究的目的是评估肝脏容积测量作为肝硬化合并肝细胞癌患者肝功能储备参数的意义。通过对44例行择期肝切除术治疗肝细胞癌的肝硬化患者术前计算机断层扫描图像计算肝脏容积。非酒精性肝硬化患者的单位体重肝脏容积显著小于酒精性肝硬化患者（20.9对26.7 cc/kg；p = 0.03）。酒精性肝硬化患者的值与正常值相当。肝硬化患者的单位体重肝脏容积与术前血清白蛋白（p < 0.01）和吲哚菁绿清除率（p = 0.02）相关。我们得出结论，通过容积测量确定肝脏萎缩可作为评估肝脏储备的参数，但不能作为肝硬化患者择期肝脏手术术后并发症的预测指标。
