McLachlan R S, Brown W F
Department of Clinical Neurological Sciences, University of Western Ontario, University Hospital, London.
Can J Neurol Sci. 1995 Feb;22(1):50-1. doi: 10.1017/s0317167100040506.
An 18-year-old man was treated from birth with chronic high dose pyridoxine (vitamin B6) up to 2000 mg per day for pyridoxine-dependent seizures. Within two years of onset of treatment, he developed a sensory neuropathy which did not progress over the following 16 years. Electrophysiological studies were consistent with a pure sensory neuronopathy expressed as centripetal degeneration of processes of the dorsal root ganglion cells.
一名18岁男性自出生起就因吡哆醇依赖性癫痫接受慢性高剂量吡哆醇（维生素B6）治疗，剂量高达每日2000毫克。在开始治疗的两年内，他出现了感觉神经病变，在接下来的16年里病情未进展。电生理研究结果与纯感觉神经元病相符，表现为背根神经节细胞突起向心性退变。
