Burech D L, Koranyi K I, Haynes R E
J Pediatr. 1976 Jun;88(6):972-4. doi: 10.1016/s0022-3476(76)81052-9.
The illnesses of 40 patients with diagnoses of septicemia, cellulitis with bacteremia, pneumonia empyema, and meningitis caused by Streptococcus pyogenes, Group A, are described. Twenty-five of 27 patients (93%) without underlying disease survived, whereas only seven of 13 children (54%) with underlying disease survived. Nine of the 25 patients who were otherwise normal and who survived these infections had prolonged, complicated illnesses. Four of these patients, and one who died, had septicemia without a focus of infection at the time of admission. Streptococcus pyogenes, Group A, although very sensitive to penicillin G and other antibiotics, can cause both severe and rapidly progressive disease in children.
本文描述了40例由A组化脓性链球菌引起的败血症、蜂窝织炎伴菌血症、肺炎脓胸和脑膜炎患者的病情。27例无基础疾病的患者中有25例（93%）存活，而13例有基础疾病的儿童中只有7例（54%）存活。在25例原本健康且在这些感染中存活下来的患者中，有9例经历了病程延长且复杂的疾病。其中4例患者以及1例死亡患者在入院时患有无感染灶的败血症。A组化脓性链球菌虽然对青霉素G和其他抗生素非常敏感，但仍可在儿童中引起严重且进展迅速的疾病。
