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一名接受青霉素预防治疗的镰状细胞贫血患者发生A组β溶血性链球菌菌血症。

Group A beta-hemolytic streptococcal bacteremia in a patient with sickle cell anemia on penicillin prophylaxis.

作者信息

LeBlanc W, Salah H, Khakoo Y

机构信息

Department of Pediatrics, College of Physicians and Surgeons of Columbia University-Harlem Hospital Center, New York, New York 10037, USA.

出版信息

J Natl Med Assoc. 1995 May;87(5):347-8.

Abstract

Serious invasive bacterial infections, particularly those due to Streptococcus pneumoniae and Hemophilus influenzae, are a well-known complication in patients with sickle cell disease. Early penicillin prophylaxis has been shown to prevent these infections and also to improve survival. This article describes a child with sickle cell anemia who, while on penicillin prophylaxis, developed a group A streptococcal bacteremia, a pathogen not commonly associated with bacteremia in sickle cell disease.

摘要

严重的侵袭性细菌感染,尤其是由肺炎链球菌和流感嗜血杆菌引起的感染,是镰状细胞病患者众所周知的并发症。早期青霉素预防已被证明可预防这些感染并提高生存率。本文描述了一名镰状细胞贫血患儿,在接受青霉素预防治疗期间发生了A组链球菌菌血症,这是一种在镰状细胞病中通常与菌血症无关的病原体。

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