LeBlanc W, Salah H, Khakoo Y
Department of Pediatrics, College of Physicians and Surgeons of Columbia University-Harlem Hospital Center, New York, New York 10037, USA.
J Natl Med Assoc. 1995 May;87(5):347-8.
Serious invasive bacterial infections, particularly those due to Streptococcus pneumoniae and Hemophilus influenzae, are a well-known complication in patients with sickle cell disease. Early penicillin prophylaxis has been shown to prevent these infections and also to improve survival. This article describes a child with sickle cell anemia who, while on penicillin prophylaxis, developed a group A streptococcal bacteremia, a pathogen not commonly associated with bacteremia in sickle cell disease.
严重的侵袭性细菌感染，尤其是由肺炎链球菌和流感嗜血杆菌引起的感染，是镰状细胞病患者众所周知的并发症。早期青霉素预防已被证明可预防这些感染并提高生存率。本文描述了一名镰状细胞贫血患儿，在接受青霉素预防治疗期间发生了A组链球菌菌血症，这是一种在镰状细胞病中通常与菌血症无关的病原体。
