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杀菌剂的环境卫生问题。I. 二硫代氨基甲酸盐类

Environmental health aspects of fungicides. I. Dithiocarbamtes.

作者信息

Fishbein L

出版信息

J Toxicol Environ Health. 1976 May;1(5):713-35. doi: 10.1080/15287397609529371.

DOI:10.1080/15287397609529371
PMID:775114
Abstract

A variety of dithiocarbamate fungicides, as well as their principal trace impurities, and metabolic or chemical degradation products are reviewed. Major focus is on their chemical and toxicological features (primarily carcinogenic, teratogenic, and mutagenic), use patterns, and residues. The compounds discussed include (1) ethylene bis(dithiocarbamated) (maneb, zineb, nabam), (2) dithiocarbamates (febram, ziram), and ("3) thiuram disulfate (thiram) and ethylene thiourea.

摘要

本文综述了多种二硫代氨基甲酸盐类杀菌剂及其主要微量杂质、代谢或化学降解产物。主要关注其化学和毒理学特性(主要是致癌性、致畸性和致突变性)、使用模式及残留情况。所讨论的化合物包括:(1)亚乙基双(二硫代氨基甲酸盐)(代森锰、代森锌、福美钠);(2)二硫代氨基甲酸盐(福美铁、福美锌);以及(3)二硫化四烷基秋兰姆(福美双)和乙撑硫脲。

相似文献

1
Environmental health aspects of fungicides. I. Dithiocarbamtes.杀菌剂的环境卫生问题。I. 二硫代氨基甲酸盐类
J Toxicol Environ Health. 1976 May;1(5):713-35. doi: 10.1080/15287397609529371.
2
Ethylenethiourea (ETU), a carcinogenic and mutagenic metabolite of ethylene bis-dithiocarbamate.乙撑硫脲(ETU),一种亚乙基双二硫代氨基甲酸盐的致癌和致突变代谢产物。
Mutat Res. 1974 Jun;26(3):189-91. doi: 10.1016/s0027-5107(74)80073-4.
3
Toxicological effects of ziram, thiram, and dithane M-45 assessed by sperm shape abnormalities in mice.
J Toxicol Environ Health. 1993 Apr;38(4):393-8. doi: 10.1080/15287399309531727.
4
Comparative effects of ten dithiocarbamate and thiuram compounds on tissue distribution and excretion of lead in rats.
Environ Res. 1987 Oct;44(1):82-93. doi: 10.1016/s0013-9351(87)80088-9.
5
[Influence of the carbamic pesticides, zineb and thiuram, on the estrus cycle and reproductive capacity of white rats].
Stud Cercet Endocrinol. 1973;24(6):491-501.
6
[Antidiuretic activity of dithiocarbamic acid derivatives].
Farmakol Toksikol. 1977 Sep-Oct;40(5):603-6.
7
[Short term effects of diets with high levels of dithiocarbamates on carbohydrate and lipid metabolism of rat liver].[高剂量二硫代氨基甲酸盐饮食对大鼠肝脏碳水化合物和脂质代谢的短期影响]
Ann Nutr Aliment. 1976;29(5):371-94.
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Thiocarbamate fungicides: reliable tools in resistance management and future outlook.硫代氨基甲酸酯类杀菌剂:抗性管理的可靠工具及未来展望。
Pest Manag Sci. 2018 Jul;74(7):1547-1551. doi: 10.1002/ps.4844. Epub 2018 Feb 23.
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Effect of dithiocarbamate fungicides and thiurams on 3H-haloperidol binding in rat brain.二硫代氨基甲酸盐类杀菌剂和福美类杀菌剂对大鼠脑内3H-氟哌啶醇结合的影响。
Arch Toxicol Suppl. 1985;8:77-9. doi: 10.1007/978-3-642-69928-3_8.
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[Effect of selected pesticides on the activity of carbonic anhydrase in vitro. II. Action of various metabolites of zineb and maneb preparations on the activity of bovine carbon anhydrase].
Rocz Panstw Zakl Hig. 1977;28(3):253-7.

引用本文的文献

1
Ethylene metabolism in Pisum sativum L.豌豆乙烯代谢
Planta. 1989 Aug;179(1):104-14. doi: 10.1007/BF00395777.
2
Developmental toxicity evaluation of zinc dimethyldithiocarbamate (Ziram) in rats.
Bull Environ Contam Toxicol. 1994 Dec;53(6):930-6. doi: 10.1007/BF00196227.
3
Ethylenebisdithiocarbamates and ethylenethiourea: possible human health hazards.乙撑双二硫代氨基甲酸盐和乙撑硫脲:对人类健康可能存在的危害。
Environ Health Perspect. 1995 Jun;103(6):568-73. doi: 10.1289/ehp.95103568.
4
The effects of carbon disulphide on rat liver microsomal mixed-function oxidases, in vivo and in vitro.二硫化碳对大鼠肝脏微粒体混合功能氧化酶的体内及体外作用。
Biochem J. 1980 Apr 15;188(1):107-12. doi: 10.1042/bj1880107.
5
Effects of nabam on developing Xenopus laevis embryos: minimum concentration, biological stability, and degradative products.代森锌对非洲爪蟾发育中胚胎的影响:最低浓度、生物稳定性及降解产物
Arch Environ Contam Toxicol. 1986 Nov;15(6):637-45. doi: 10.1007/BF01054910.
6
Inhibition of hepatic epoxide hydrolase and glutathione S-transferase in rats by bis(dimethyldithiocarbamato) zinc (ziram).
Bull Environ Contam Toxicol. 1986 Jul;37(1):53-4. doi: 10.1007/BF01607728.
7
Toxicity of thiram (tetramethylthiuram disulfide) to mink and European ferrets.
Bull Environ Contam Toxicol. 1987 Apr;38(4):618-26. doi: 10.1007/BF01608594.
8
Environmental and biological monitoring of exposure to ethylenebisdithiocarbamate fungicides and ethylenethiourea.对亚乙基双二硫代氨基甲酸盐类杀菌剂和乙撑硫脲暴露的环境与生物监测。
Br J Ind Med. 1990 Mar;47(3):203-6. doi: 10.1136/oem.47.3.203.
9
The study of leucine and methionine transport in the gut of rats intoxicated with thiram.
Arch Toxicol. 1992;66(4):267-71. doi: 10.1007/BF02307172.
10
The toxicity of manganese ethylenebisdithiocarbamate to the adult newt, Triturus cristatus.亚乙基双二硫代氨基甲酸锰对成年冠欧螈的毒性。
Bull Environ Contam Toxicol. 1978 Aug;20(2):261-7. doi: 10.1007/BF01683518.