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用于检测感染人类免疫缺陷病毒患者肠道细菌病原体的肠道活检标本培养和粪便培养。柏林腹泻/消瘦综合征研究组。

Culture of intestinal biopsy specimens and stool culture for detection of bacterial enteropathogens in patients infected with human immunodeficiency virus. The Berlin Diarrhea/Wasting Syndrome Study Group.

作者信息

Liesenfeld O, Schneider T, Schmidt W, Sandforth J, Weinke T, Zeitz M, Riecken E O, Ullrich R

机构信息

Institute of Medical Microbiology and Infectious Diseases Immunology, Free University of Berlin, Germany.

出版信息

J Clin Microbiol. 1995 Mar;33(3):745-7. doi: 10.1128/jcm.33.3.745-747.1995.

Abstract

The diagnostic yields of stool cultures and biopsy specimens for the detection of enteric bacterial pathogens in 213 human immunodeficiency virus-infected patients were compared. Forty-five percent (19 of 42) of the pathogens were detected exclusively by stool culture, 2% (1 of 42) of the isolates were detected exclusively by culture of biopsy specimens, and 53% (22 of 42) were detected by both methods. Repeated stool cultures remain the most important means of diagnosing enteric bacterial pathogens, which were encountered in 20% (40 of 213) of all patients. The additional culture of biopsy specimens should be reserved for patients with suspected mycobacteriosis.

摘要

对213例人类免疫缺陷病毒感染患者的粪便培养物和活检标本进行检测,以比较检测肠道细菌病原体的诊断率。45%(42例中的19例)的病原体仅通过粪便培养检测到,2%(42例中的1例)的分离株仅通过活检标本培养检测到,53%(42例中的22例)通过两种方法均检测到。重复粪便培养仍然是诊断肠道细菌病原体的最重要手段,在所有患者中有20%(213例中的40例)出现了此类病原体。活检标本的额外培养应仅用于疑似分枝杆菌病的患者。

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