Stone B L, Cohn D L, Kane M S, Hildred M V, Wilson M L, Reves R R
Denver Disease Control Service, Denver Health and Hospital, Colorado 80204.
J Clin Microbiol. 1994 Mar;32(3):841-2. doi: 10.1128/jcm.32.3.841-842.1994.
For 273 patients evaluated for disseminated Mycobacterium avium complex infection, a total of 1,047 mycobacterial blood cultures (MBCs) were submitted; the M. avium complex was recovered from 140 (13%) of the specimens. Results for the paired MBCs were highly concordant: in 392 of 462 (85%) culture sets, both MBCs were negative, in 53 of 462 (11%) sets, both MBCs were positive, and in only 17 of 462 (4%) sets was one culture positive and the other negative. Acid-fast smears were done on sediments from 671 specimens; smears were positive for 4 of 98 (4%) cultures that grew the M. avium complex. A single MBC should be obtained and then repeated if negative and disseminated M. avium complex infection is still clinically suspected. Use of direct acid-fast smears of sediments is not a reliable means of detecting mycobacteremia.
对273例播散性鸟分枝杆菌复合群感染患者进行评估，共送检了1047份分枝杆菌血培养（MBC）标本；140份（13%）标本培养出鸟分枝杆菌复合群。配对的MBC结果高度一致：462组培养中，392组（85%）两份MBC均为阴性，462组中有53组（11%）两份MBC均为阳性，462组中仅有17组（4%）一份培养阳性而另一份阴性。对671份标本的沉淀物进行了抗酸涂片检查；在培养出鸟分枝杆菌复合群的98份培养物中，4份（4%）涂片呈阳性。应采集一份MBC标本，如果结果为阴性且仍临床怀疑播散性鸟分枝杆菌复合群感染，则需重复送检。对沉淀物进行直接抗酸涂片检查并非检测分枝杆菌血症的可靠方法。
