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出生后发育过程中染色质和DNA依赖性RNA聚合酶III的模板活性(作者译)

[Template activity of chromatin and DNA-dependent RNA polymerase III during postnatal development (author's transl)].

作者信息

van der Meulen N, Lipp K, Wenske G, Stössel R

出版信息

Klin Wochenschr. 1976 May 1;54(9):449-50. doi: 10.1007/BF01470932.

Abstract

The template-activity of chromatin isolated from liver nuclei of developing rats increases sharply at birth and decreases remarkable until the 10th day. Between the 10th and the 40th day a slow increase was shown in template activity of chromatin tested with purified E.-coli RNA-polymerase (EC 2.7.7.6). We correlated these findings with changes of RNA-polymerase III-activity in rat liver during development.

摘要

从发育中大鼠肝脏细胞核分离出的染色质模板活性在出生时急剧增加,到第10天显著下降。在第10天至第40天之间,用纯化的大肠杆菌RNA聚合酶(EC 2.7.7.6)检测的染色质模板活性呈缓慢增加。我们将这些发现与大鼠肝脏发育过程中RNA聚合酶III活性的变化相关联。

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