Yeast mutants resistant to basic fuchsin: a genetic approach to the integration of nuclear and mitochondrial information.
作者信息
Barrere G, Mounolou J C
出版信息
Mutat Res. 1976 Apr;35(1):39-52. doi: 10.1016/0027-5107(76)90167-6.
PMID:775323
Abstract
In yeast, basic fuchsin both inhibits mitochondrial functions and is a potent mutagen for the mitochondrial genome. A genetic analysis of two mutants resistant to the dye indicate that: (1) resistance is specified by a nuclear gene; (2) the onset of resistance in sensitive cells is controlled by the mitochondrial genome; and (3) sensitive mitochondrial structures can be carried over for many cell generations in the presence of a resistant nuclear genotype.
摘要
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